RHBDL2 promotes the proliferation, migration, and invasion of pancreatic cancer by stabilizing the N1ICD via the OTUD7B and activating the Notch signaling pathway

Pancreatic cancer (PC) is one of the most malignant types of cancer, and is characterized by early metastasis, limited response to chemotherapeutics, and poor prognosis. Therefore, there is an urgent need to explore new therapeutic strategies for PC treatment. Human rhomboid-like 2 (RHBDL2) is diffe...

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Detalles Bibliográficos
Autores principales: Chen, Shiyu, Cai, Kun, Zheng, Dijie, Liu, Yanqing, Li, Lin, He, Zhiwei, Sun, Chengyi, Yu, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646733/
https://www.ncbi.nlm.nih.gov/pubmed/36351890
http://dx.doi.org/10.1038/s41419-022-05379-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646733/
https://www.ncbi.nlm.nih.gov/pubmed/36351890
http://dx.doi.org/10.1038/s41419-022-05379-3

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