Harnessing the synergy of perfusable muscle flap matrix and adipose-derived stem cells for prevascularization and macrophage polarization to reconstruct volumetric muscle loss

Muscle flaps must have a strong vascular network to support a large tissue volume and ensure successful engraftment. We developed porcine stomach musculofascial flap matrix (PDSF) comprising extracellular matrix (ECM) and intact vasculature. PDSF had a dominant vascular pedicle, microcirculatory ves...

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Detalles Bibliográficos
Autores principales: Zhang, Qixu, Chiu, Yulun, Chen, Youbai, Wu, Yewen, Dunne, Lina W., Largo, Rene D., Chang, Edward I., Adelman, David M., Schaverien, Mark V., Butler, Charles E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646752/
https://www.ncbi.nlm.nih.gov/pubmed/36382023
http://dx.doi.org/10.1016/j.bioactmat.2022.10.023

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