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Oxidative degradation of dihydrofolate reductase increases CD38-mediated ferroptosis susceptibility

High expression of CD38 in tissues is a characteristic of aging, resulting in a decline in nicotinamide adenine dinucleotide (NAD) and increasing cellular reactive oxygen species (ROS). However, whether CD38 increases susceptibility to ferroptosis remains largely unexplored. Our previous study showe...

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Detalles Bibliográficos
Autores principales:	Ma, Yingying, Yi, Meiqi, Wang, Weixuan, Liu, Xiaohui, Wang, Qingtao, Liu, Chongdong, Chen, Yuling, Deng, Haiteng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646779/ https://www.ncbi.nlm.nih.gov/pubmed/36351893 http://dx.doi.org/10.1038/s41419-022-05383-7

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