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Influence of the coiling porosity on the risk reduction of the cerebral aneurysm rupture: computational study

The formation and progress of cerebral aneurysm is highly associated with hemodynamic factors and blood flow feature. In this study, comprehensive efforts are done to investigate the blood hemodynamic effects on the creation and growth of the Internal Carotid Artery. The computational fluid dynamic...

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Autores principales: Sheidani, Armin, Barzegar Gerdroodbary, M., Poozesh, Amin, Sabernaeemi, Amir, Salavatidezfouli, Sajad, Hajisharifi, Arash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646831/
https://www.ncbi.nlm.nih.gov/pubmed/36352253
http://dx.doi.org/10.1038/s41598-022-23745-1
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author Sheidani, Armin
Barzegar Gerdroodbary, M.
Poozesh, Amin
Sabernaeemi, Amir
Salavatidezfouli, Sajad
Hajisharifi, Arash
author_facet Sheidani, Armin
Barzegar Gerdroodbary, M.
Poozesh, Amin
Sabernaeemi, Amir
Salavatidezfouli, Sajad
Hajisharifi, Arash
author_sort Sheidani, Armin
collection PubMed
description The formation and progress of cerebral aneurysm is highly associated with hemodynamic factors and blood flow feature. In this study, comprehensive efforts are done to investigate the blood hemodynamic effects on the creation and growth of the Internal Carotid Artery. The computational fluid dynamic method is used for the visualization of the bloodstream inside the aneurysm. Transitional, non-Newtonian and incompressible conditions are considered for solving the Navier–Stokes equation to achieve the high-risk region on the aneurysm wall. OSI and WSS of the aneurysm wall are compared within different blood flow stages. The effects of blood viscosity and coiling treatment on these factors are presented in this work. Our study shows that in male patients (HCT = 0.45), changing the porosity of coiling from 0.89 with 0.79 would decreases maximum OSI up to 75% (in maximum acceleration). However, this effect is limited to about 45% for female patients (HCT = 0.35).
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spelling pubmed-96468312022-11-15 Influence of the coiling porosity on the risk reduction of the cerebral aneurysm rupture: computational study Sheidani, Armin Barzegar Gerdroodbary, M. Poozesh, Amin Sabernaeemi, Amir Salavatidezfouli, Sajad Hajisharifi, Arash Sci Rep Article The formation and progress of cerebral aneurysm is highly associated with hemodynamic factors and blood flow feature. In this study, comprehensive efforts are done to investigate the blood hemodynamic effects on the creation and growth of the Internal Carotid Artery. The computational fluid dynamic method is used for the visualization of the bloodstream inside the aneurysm. Transitional, non-Newtonian and incompressible conditions are considered for solving the Navier–Stokes equation to achieve the high-risk region on the aneurysm wall. OSI and WSS of the aneurysm wall are compared within different blood flow stages. The effects of blood viscosity and coiling treatment on these factors are presented in this work. Our study shows that in male patients (HCT = 0.45), changing the porosity of coiling from 0.89 with 0.79 would decreases maximum OSI up to 75% (in maximum acceleration). However, this effect is limited to about 45% for female patients (HCT = 0.35). Nature Publishing Group UK 2022-11-09 /pmc/articles/PMC9646831/ /pubmed/36352253 http://dx.doi.org/10.1038/s41598-022-23745-1 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Sheidani, Armin
Barzegar Gerdroodbary, M.
Poozesh, Amin
Sabernaeemi, Amir
Salavatidezfouli, Sajad
Hajisharifi, Arash
Influence of the coiling porosity on the risk reduction of the cerebral aneurysm rupture: computational study
title Influence of the coiling porosity on the risk reduction of the cerebral aneurysm rupture: computational study
title_full Influence of the coiling porosity on the risk reduction of the cerebral aneurysm rupture: computational study
title_fullStr Influence of the coiling porosity on the risk reduction of the cerebral aneurysm rupture: computational study
title_full_unstemmed Influence of the coiling porosity on the risk reduction of the cerebral aneurysm rupture: computational study
title_short Influence of the coiling porosity on the risk reduction of the cerebral aneurysm rupture: computational study
title_sort influence of the coiling porosity on the risk reduction of the cerebral aneurysm rupture: computational study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646831/
https://www.ncbi.nlm.nih.gov/pubmed/36352253
http://dx.doi.org/10.1038/s41598-022-23745-1
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