Cryo-EM reveals the architecture of the PELP1-WDR18 molecular scaffold

PELP1 (Proline-, Glutamic acid-, Leucine-rich protein 1) is a large scaffolding protein that functions in many cellular pathways including steroid receptor (SR) coactivation, heterochromatin maintenance, and ribosome biogenesis. PELP1 is a proto-oncogene whose expression is upregulated in many human...

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Detalles Bibliográficos
Autores principales: Gordon, Jacob, Chapus, Fleur L., Viverette, Elizabeth G., Williams, Jason G., Deterding, Leesa J., Krahn, Juno M., Borgnia, Mario J., Rodriguez, Joseph, Warren, Alan J., Stanley, Robin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646879/
https://www.ncbi.nlm.nih.gov/pubmed/36351913
http://dx.doi.org/10.1038/s41467-022-34610-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646879/
https://www.ncbi.nlm.nih.gov/pubmed/36351913
http://dx.doi.org/10.1038/s41467-022-34610-0

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