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Empagliflozin suppresses urinary mitochondrial DNA copy numbers and interleukin-1β in type 2 diabetes patients

Sodium-glucose co-transporter 2 (SGLT2) inhibitors improve cardiovascular and renal outcomes in type 2 diabetes mellitus (T2DM) patients. However, the mechanisms by which SGLT2 inhibitors improve the clinical outcomes remain elusive. We evaluated whether empagliflozin, an SGLT2 inhibitor, ameliorate...

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Detalles Bibliográficos
Autores principales: Lee, Haekyung, Kim, Hyoungnae, Jeon, Jin Seok, Noh, Hyunjin, Park, Rojin, Byun, Dong Won, Kim, Hye Jeong, Suh, Kyoil, Park, Hyeong Kyu, Kwon, Soon Hyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646895/
https://www.ncbi.nlm.nih.gov/pubmed/36351983
http://dx.doi.org/10.1038/s41598-022-22083-6