Cargando…

Empagliflozin suppresses urinary mitochondrial DNA copy numbers and interleukin-1β in type 2 diabetes patients

Sodium-glucose co-transporter 2 (SGLT2) inhibitors improve cardiovascular and renal outcomes in type 2 diabetes mellitus (T2DM) patients. However, the mechanisms by which SGLT2 inhibitors improve the clinical outcomes remain elusive. We evaluated whether empagliflozin, an SGLT2 inhibitor, ameliorate...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lee, Haekyung, Kim, Hyoungnae, Jeon, Jin Seok, Noh, Hyunjin, Park, Rojin, Byun, Dong Won, Kim, Hye Jeong, Suh, Kyoil, Park, Hyeong Kyu, Kwon, Soon Hyo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646895/ https://www.ncbi.nlm.nih.gov/pubmed/36351983 http://dx.doi.org/10.1038/s41598-022-22083-6

Ejemplares similares

Effect of bariatric surgery on circulating and urinary mitochondrial DNA copy numbers in obesity with or without diabetes
por: Seo, Mihae, et al.
Publicado: (2020)

IgA nephropathy is associated with elevated urinary mitochondrial DNA copy numbers
por: Yu, Byung Chul, et al.
Publicado: (2019)

Association between blood pressure and the risk of chronic kidney disease in treatment-naïve hypertensive patients
por: Lee, Haekyung, et al.
Publicado: (2022)

Effect of diabetes on exosomal miRNA profile in patients with obesity
por: Kim, Hyoshik, et al.
Publicado: (2020)

Metformin inhibits chronic kidney disease‐induced DNA damage and senescence of mesenchymal stem cells
por: Kim, Hyoungnae, et al.
Publicado: (2021)

The circulating exosomal microRNAs related to albuminuria in patients with diabetic nephropathy
por: Kim, Hyoungnae, et al.
Publicado: (2019)

Association between Beta2-Adrenergic Receptor Agonists and the Risk of Vascular Complications in Diabetic Patients: A Population-Based Cohort Study
por: Lee, Hee Jeong, et al.
Publicado: (2019)

Circulating miRNAs in extracellular vesicles related to treatment response in patients with idiopathic membranous nephropathy
por: Sun, In O., et al.
Publicado: (2022)

Impaired fasting glucose and development of chronic kidney disease in non-diabetic population: a Mendelian randomization study
por: Kim, Hyoungnae, et al.
Publicado: (2020)

microRNA in Extracellular Vesicles Released by Damaged Podocytes Promote Apoptosis of Renal Tubular Epithelial Cells
por: Jeon, Jin Seok, et al.
Publicado: (2020)

Epicardial adipose tissue radiodensity is associated with all-cause mortality in patients undergoing hemodialysis
por: Kwon, Seong Soon, et al.
Publicado: (2021)

Association between Serum Cystatin C and Vascular Complications in Type 2 Diabetes Mellitus without Nephropathy
por: Kim, Hye Jeong, et al.
Publicado: (2018)

SUN-156 Exosomal MicroRNA Profile in Korean Obese Subjects with Prediabetes and Those with Type 2 Diabetes Mellitus
por: Park, Hyeong-Kyu, et al.
Publicado: (2019)

Association of free thyroxine with obstructive lung pattern in euthyroid middle-aged subjects: A population-based study
por: Kim, Hye Jeong, et al.
Publicado: (2022)

Subclinical thyroid dysfunction and chronic kidney disease: a nationwide population-based study
por: Kim, Hye Jeong, et al.
Publicado: (2023)

Risk of carotid plaques according to triglyceride-glucose index stratified by thyroid function: A cross-sectional study
por: Kim, Hye Jeong, et al.
Publicado: (2022)

Shear wave elasticity by tracing total nodule showed high reproducibility and concordance with fibrosis in thyroid cancer
por: Yoo, Myung Hi, et al.
Publicado: (2020)

Efficacy of Differential Diagnosis of Thyroid Nodules by Shear Wave Elastography—the Stiffness Map
por: Yoo, Myung Hi, et al.
Publicado: (2021)

Efficacy of Differential Diagnosis of Thyroid Nodules by Shear Wave Elastography, the Stiffness Map
por: Yoo, Myung Hi, et al.
Publicado: (2021)

Novel mutations in patients with X-linked Alport syndrome: Two case reports
por: Oh, Songhee, et al.
Publicado: (2019)

Efficacy of Shear-Wave Elastography for Detecting Postoperative Cervical Lymph Node Metastasis in Papillary Thyroid Carcinoma
por: Kim, Hye Jeong, et al.
Publicado: (2018)

Pericoronary fat attenuation index in computed tomography angiography is associated with mortality in end-stage renal disease
por: Cho, Nam-Jun, et al.
Publicado: (2022)

Metformin use and cardiovascular outcomes in patients with diabetes and chronic kidney disease: a nationwide cohort study
por: Kim, Min-Ho, et al.
Publicado: (2021)

Chronic kidney disease (CKD) patients are exposed to more proton pump inhibitor (PPI)s compared to non-CKD patients
por: Lee, Hee Jeong, et al.
Publicado: (2018)

Correction: Chronic kidney disease (CKD) patients are exposed to more proton pump inhibitor (PPI)s compared to non-CKD patients
por: Lee, Hee Jeong, et al.
Publicado: (2018)

Association between Sarcopenia, Sarcopenic Obesity, and Chronic Disease in Korean Elderly
por: Lim, Hee-Sook, et al.
Publicado: (2018)

Sirt1–hypoxia‐inducible factor‐1α interaction is a key mediator of tubulointerstitial damage in the aged kidney
por: Ryu, Dong Ryeol, et al.
Publicado: (2019)

Utility of shear wave elastography to detect papillary thyroid carcinoma in thyroid nodules: efficacy of the standard deviation elasticity
por: Kim, Hye Jeong, et al.
Publicado: (2019)

Age and sex specific target of blood pressure for the prevention of cardiovascular event among the treatment naive hypertensive patients
por: Kim, Hyoungnae, et al.
Publicado: (2020)

Copy number variations (CNVs) identified in Korean individuals
por: Kang, Tae-Wook, et al.
Publicado: (2008)

Effect of treatment on urinary kidney injury molecule-1 in IgA nephropathy
por: Seo, Mi Seon, et al.
Publicado: (2013)

Triiodothyronine Levels Are Independently Associated with Metabolic Syndrome in Euthyroid Middle-Aged Subjects
por: Kim, Hye Jeong, et al.
Publicado: (2016)

Copy Number Variation of Age-Related Macular Degeneration Relevant Genes in the Korean Population
por: Park, Jung Hyun, et al.
Publicado: (2012)

Urinary Exosomal and cell-free DNA Detects Somatic Mutation and Copy Number Alteration in Urothelial Carcinoma of Bladder
por: Lee, Dong Hyeon, et al.
Publicado: (2018)

THU287 Comparison Of Renal Protective Effects Between SGLT2 Inhibitors And DPP4 Inhibitors In Real-World Clinical Practice
por: Park, Hyeong-Kyu, et al.
Publicado: (2023)

Identification of copy number variations and common deletion polymorphisms in cattle
por: Bae, Joon Seol, et al.
Publicado: (2010)

Validation of an international prediction model including the Oxford classification in Korean patients with IgA nephropathy
por: Hwang, Dohui, et al.
Publicado: (2021)

Minor Glomerular Abnormalities are Associated with Deterioration of Long-Term Kidney Function and Mitochondrial Injury
por: Yu, Byung Chul, et al.
Publicado: (2019)

Empagliflozin Reduces Interleukin-6 Levels in Patients with Heart Failure
por: Gotzmann, Michael, et al.
Publicado: (2023)

Peripheral Mitochondrial DNA Copy Number is Increased in Korean Attention-Deficit Hyperactivity Disorder Patients
por: Kim, Johanna Inhyang, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_2d4i07trd4061d3djf7uuvku5s