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Nicking mechanism underlying the DNA phosphorothioate-sensing antiphage defense by SspE

DNA phosphorothioate (PT) modification, with a nonbridging phosphate oxygen substituted by sulfur, represents a widespread epigenetic marker in prokaryotes and provides protection against genetic parasites. In the PT-based defense system Ssp, SspABCD confers a single-stranded PT modification of host...

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Detalles Bibliográficos
Autores principales: Gao, Haiyan, Gong, Xinqi, Zhou, Jinchuan, Zhang, Yubing, Duan, Jinsong, Wei, Yue, Chen, Liuqing, Deng, Zixin, Wang, Jiawei, Chen, Shi, Wu, Geng, Wang, Lianrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646914/
https://www.ncbi.nlm.nih.gov/pubmed/36351933
http://dx.doi.org/10.1038/s41467-022-34505-0