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Forced expression of the non-coding RNA miR-17∼92 restores activation and function in CD28-deficient CD4(+) T cells

CD28 provides the prototypical costimulatory signal required for productive T-cell activation. Known molecular consequences of CD28 costimulation are mostly based on studies of protein signaling molecules. The microRNA cluster miR-17∼92 is induced by T cell receptor stimulation and further enhanced...

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Detalles Bibliográficos
Autores principales:	Dölz, Marianne, Hasiuk, Marko, Gagnon, John D., Kornete, Mara, Marone, Romina, Bantug, Glenn, Kageyama, Robin, Hess, Christoph, Ansel, K. Mark, Seyres, Denis, Roux, Julien, Jeker, Lukas T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646923/ https://www.ncbi.nlm.nih.gov/pubmed/36388982 http://dx.doi.org/10.1016/j.isci.2022.105372

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