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Single cell sequencing maps skeletal muscle cellular diversity as disease severity increases in dystrophic mouse models
Duchenne muscular dystrophy (DMD) is caused by out-of-frame mutations in the DMD gene resulting in the absence of a functional dystrophin protein, leading to a devastating and progressive lethal muscle-wasting disease. Little is known about cellular heterogeneity as disease severity increases. Advan...
Autores principales: | Saleh, Kholoud K., Xi, Haibin, Switzler, Corey, Skuratovsky, Emily, Romero, Matthew A., Chien, Peggie, Gibbs, Devin, Gane, Lily, Hicks, Michael R., Spencer, Melissa J., Pyle, April D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9646951/ https://www.ncbi.nlm.nih.gov/pubmed/36388984 http://dx.doi.org/10.1016/j.isci.2022.105415 |
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