Anatomical barriers against SARS-CoV-2 neuroinvasion at vulnerable interfaces visualized in deceased COVID-19 patients

Can SARS-CoV-2 hitchhike on the olfactory projection and take a direct and short route from the nose into the brain? We reasoned that the neurotropic or neuroinvasive capacity of the virus, if it exists, should be most easily detectable in individuals who died in an acute phase of the infection. Her...

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Detalles Bibliográficos
Autores principales: Khan, Mona, Clijsters, Marnick, Choi, Sumin, Backaert, Wout, Claerhout, Michiel, Couvreur, Floor, Van Breda, Laure, Bourgeois, Florence, Speleman, Kato, Klein, Sam, Van Laethem, Johan, Verstappen, Gill, Dereli, Ayse Sumeyra, Yoo, Seung-Jun, Zhou, Hai, Dan Do, Thuc Nguyen, Jochmans, Dirk, Laenen, Lies, Debaveye, Yves, De Munter, Paul, Gunst, Jan, Jorissen, Mark, Lagrou, Katrien, Meersseman, Philippe, Neyts, Johan, Thal, Dietmar Rudolf, Topsakal, Vedat, Vandenbriele, Christophe, Wauters, Joost, Mombaerts, Peter, Van Gerven, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Inc. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647025/
https://www.ncbi.nlm.nih.gov/pubmed/36446381
http://dx.doi.org/10.1016/j.neuron.2022.11.007

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