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How long do revised and multiply revised hip replacements last? A retrospective observational study of the National Joint Registry

BACKGROUND: Hip replacements are common and effective operations but patients that undergo this intervention are at risk of the replacements failing, requiring costly and often complex revision surgery with poorer outcomes than primary surgery. There is paucity of reliable data examining the treatme...

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Autores principales: Deere, Kevin, Whitehouse, Michael R, Kunutsor, Setor K, Sayers, Adrian, Mason, James, Blom, Ashley W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647039/
https://www.ncbi.nlm.nih.gov/pubmed/36394063
http://dx.doi.org/10.1016/S2665-9913(22)00097-2
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author Deere, Kevin
Whitehouse, Michael R
Kunutsor, Setor K
Sayers, Adrian
Mason, James
Blom, Ashley W
author_facet Deere, Kevin
Whitehouse, Michael R
Kunutsor, Setor K
Sayers, Adrian
Mason, James
Blom, Ashley W
author_sort Deere, Kevin
collection PubMed
description BACKGROUND: Hip replacements are common and effective operations but patients that undergo this intervention are at risk of the replacements failing, requiring costly and often complex revision surgery with poorer outcomes than primary surgery. There is paucity of reliable data examining the treatment pathway for hip replacements over the life of the patient in terms of risk of revision and re-revisions. We aim to provide detailed information on the longevity of hip revision surgery. METHODS: We did a retrospective observational registry-based study of the National Joint Registry, using data on hip replacements from all participating hospitals in England and Wales, UK. We included data on all first revisions, with an identifiable primary procedure, with osteoarthritis as the sole indication for the original primary procedure. Kaplan-Meier estimates were used to determine the cumulative probability of revision and subsequent re-revision after primary hip replacement. Analyses were stratified by age and gender, and the influence of time from first to second revision on the risk of further revision was explored. FINDINGS: Between April 1, 2003, and Dec 31, 2019, there were 29 010 revision hip replacements with a linked primary episode. Revision rates of revision hip replacements were higher in patients younger than 55 years than in older age groups. After revision of primary total hip replacement, 21·3% (95% CI 18·6–24·4) of first revisions were revised again within 15 years, 22·3% (20·3–24·4) of second revisions were revised again within 7 years, and 22·3% (18·3–27·0) of third revisions were revised again within 3 years. After revision of hip resurfacing, 23·7% (95% CI 19·6–28·5) of these revisions were revised again within 15 years, 21·0% (17·0–25·8) of second revisions were revised again within 7 years, and 19·3% (11·9–30·4) of third revisions were revised again within 3 years. A shorter time between revision episodes was associated with earlier subsequent revision. INTERPRETATION: Younger patients are at an increased risk of multiple revisions. Patients who undergo a revision have a steadily increasing risk of further revision the more procedures they undergo, and each subsequent revision lasts for approximately half the time of the previous one. Although hip replacements are effective for improving pain and function and usually last a remarkably long time, if they are revised, successive revisions are progressively and markedly less successful. FUNDING: NIHR Biomedical Research Centre at the University Hospitals Bristol and Weston NHS Foundation Trust and the University of Bristol, Healthcare Quality Improvement Partnership; and the National Joint Registry.
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spelling pubmed-96470392022-11-14 How long do revised and multiply revised hip replacements last? A retrospective observational study of the National Joint Registry Deere, Kevin Whitehouse, Michael R Kunutsor, Setor K Sayers, Adrian Mason, James Blom, Ashley W Lancet Rheumatol Articles BACKGROUND: Hip replacements are common and effective operations but patients that undergo this intervention are at risk of the replacements failing, requiring costly and often complex revision surgery with poorer outcomes than primary surgery. There is paucity of reliable data examining the treatment pathway for hip replacements over the life of the patient in terms of risk of revision and re-revisions. We aim to provide detailed information on the longevity of hip revision surgery. METHODS: We did a retrospective observational registry-based study of the National Joint Registry, using data on hip replacements from all participating hospitals in England and Wales, UK. We included data on all first revisions, with an identifiable primary procedure, with osteoarthritis as the sole indication for the original primary procedure. Kaplan-Meier estimates were used to determine the cumulative probability of revision and subsequent re-revision after primary hip replacement. Analyses were stratified by age and gender, and the influence of time from first to second revision on the risk of further revision was explored. FINDINGS: Between April 1, 2003, and Dec 31, 2019, there were 29 010 revision hip replacements with a linked primary episode. Revision rates of revision hip replacements were higher in patients younger than 55 years than in older age groups. After revision of primary total hip replacement, 21·3% (95% CI 18·6–24·4) of first revisions were revised again within 15 years, 22·3% (20·3–24·4) of second revisions were revised again within 7 years, and 22·3% (18·3–27·0) of third revisions were revised again within 3 years. After revision of hip resurfacing, 23·7% (95% CI 19·6–28·5) of these revisions were revised again within 15 years, 21·0% (17·0–25·8) of second revisions were revised again within 7 years, and 19·3% (11·9–30·4) of third revisions were revised again within 3 years. A shorter time between revision episodes was associated with earlier subsequent revision. INTERPRETATION: Younger patients are at an increased risk of multiple revisions. Patients who undergo a revision have a steadily increasing risk of further revision the more procedures they undergo, and each subsequent revision lasts for approximately half the time of the previous one. Although hip replacements are effective for improving pain and function and usually last a remarkably long time, if they are revised, successive revisions are progressively and markedly less successful. FUNDING: NIHR Biomedical Research Centre at the University Hospitals Bristol and Weston NHS Foundation Trust and the University of Bristol, Healthcare Quality Improvement Partnership; and the National Joint Registry. Elsevier Ltd 2022-06-23 /pmc/articles/PMC9647039/ /pubmed/36394063 http://dx.doi.org/10.1016/S2665-9913(22)00097-2 Text en © 2022 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Articles
Deere, Kevin
Whitehouse, Michael R
Kunutsor, Setor K
Sayers, Adrian
Mason, James
Blom, Ashley W
How long do revised and multiply revised hip replacements last? A retrospective observational study of the National Joint Registry
title How long do revised and multiply revised hip replacements last? A retrospective observational study of the National Joint Registry
title_full How long do revised and multiply revised hip replacements last? A retrospective observational study of the National Joint Registry
title_fullStr How long do revised and multiply revised hip replacements last? A retrospective observational study of the National Joint Registry
title_full_unstemmed How long do revised and multiply revised hip replacements last? A retrospective observational study of the National Joint Registry
title_short How long do revised and multiply revised hip replacements last? A retrospective observational study of the National Joint Registry
title_sort how long do revised and multiply revised hip replacements last? a retrospective observational study of the national joint registry
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647039/
https://www.ncbi.nlm.nih.gov/pubmed/36394063
http://dx.doi.org/10.1016/S2665-9913(22)00097-2
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