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DNA methylation topology differentiates between normal and malignant in cell models, resected human tissues, and exfoliated sputum cells of lung epithelium

BACKGROUND: Global DNA hypomethylation is a prominent feature of cancer cells including lung cancer, that has not been widely explored towards cancer diagnosis. In this study we assess the comparative distribution of global DNA methylation in normal cells versus cancer cells in various specimen mode...

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Detalles Bibliográficos
Autores principales:	Tajbakhsh, Jian, Mortazavi, Fariborz, Gupta, Nirdesh K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647067/ https://www.ncbi.nlm.nih.gov/pubmed/36387135 http://dx.doi.org/10.3389/fonc.2022.991120

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