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The paradox of immune checkpoint inhibition re-activating tuberculosis

By attenuating T-cell activation, immune checkpoints (ICs) limit optimal anti-tumour responses and IC inhibition (ICI) has emerged as a new therapy for a broad range of cancers. T-cell responses are indispensable to tuberculosis (TB) immunity in humans. However, boosting T-cell immunity in cancer pa...

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Detalles Bibliográficos
Autores principales:	Ahmed, Mohamed, Tezera, Liku B., Elkington, Paul T., Leslie, Alasdair J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	European Respiratory Society 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647068/ https://www.ncbi.nlm.nih.gov/pubmed/35595321 http://dx.doi.org/10.1183/13993003.02512-2021

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