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Successful management of mucormycosis infection secondary to motor vehicle accident in a healthy adolescent: A case report

Mucormycosis in healthy adolescents is a rare etiology of infection that does not have a commonly known protocol for management. This report describes an adolescent male who developed soft tissue mucormycosis secondary to a motor vehicle accident with severe lower extremity injuries. Treatment invol...

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Detalles Bibliográficos
Autores principales: Shah, Hemali, Chisena, Ernest, Nguyen, Brittany, Tristram, Debra, Bialowas, Christie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647094/
https://www.ncbi.nlm.nih.gov/pubmed/36393995
http://dx.doi.org/10.1016/j.mmcr.2022.10.004
Descripción
Sumario:Mucormycosis in healthy adolescents is a rare etiology of infection that does not have a commonly known protocol for management. This report describes an adolescent male who developed soft tissue mucormycosis secondary to a motor vehicle accident with severe lower extremity injuries. Treatment involved topical amphotericin B washouts and beads, serial aggressive debridement, and isavuconazole. To our knowledge, this is one of few documented cases of successful lower extremity salvage in an immunocompetent adolescent infected with mucormycosis and treated with isavuconazole.