Upregulation of GLT25D1 in Hepatic Stellate Cells Promotes Liver Fibrosis via the TGF-β1/SMAD3 Pathway In Vivo and In vitro

BACKGROUND AND AIMS: Collagen β(1-O) galactosyltransferase 25 domain 1 (GLT25D1) is associated with collagen production and glycosylation, and its knockout in mice results in embryonic death. However, its role in liver fibrosis remains elusive, particularly in hepatic stellate cells (HSCs), the prim...

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Detalles Bibliográficos
Autores principales: Wang, Shiwei, He, Lingling, Xiao, Fan, Gao, Meixin, Wei, Herui, Yang, Junru, Shu, Yang, Zhang, Fuyang, Ye, Xiaohui, Li, Ping, Hao, Xiaohua, Zhou, Xingang, Wei, Hongshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: XIA & HE Publishing Inc. 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647113/
https://www.ncbi.nlm.nih.gov/pubmed/36406310
http://dx.doi.org/10.14218/JCTH.2022.00005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647113/
https://www.ncbi.nlm.nih.gov/pubmed/36406310
http://dx.doi.org/10.14218/JCTH.2022.00005

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