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Upregulation of GLT25D1 in Hepatic Stellate Cells Promotes Liver Fibrosis via the TGF-β1/SMAD3 Pathway In Vivo and In vitro
BACKGROUND AND AIMS: Collagen β(1-O) galactosyltransferase 25 domain 1 (GLT25D1) is associated with collagen production and glycosylation, and its knockout in mice results in embryonic death. However, its role in liver fibrosis remains elusive, particularly in hepatic stellate cells (HSCs), the prim...
Autores principales: | Wang, Shiwei, He, Lingling, Xiao, Fan, Gao, Meixin, Wei, Herui, Yang, Junru, Shu, Yang, Zhang, Fuyang, Ye, Xiaohui, Li, Ping, Hao, Xiaohua, Zhou, Xingang, Wei, Hongshan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
XIA & HE Publishing Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647113/ https://www.ncbi.nlm.nih.gov/pubmed/36406310 http://dx.doi.org/10.14218/JCTH.2022.00005 |
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