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Anticonvulsant effects of ivermectin on pentylenetetrazole- and maximal electroshock-induced seizures in mice: the role of GABAergic system and K(ATP) channels

INTRODUCTION: Ivermectin (IVM) is an antiparasitic medicine that exerts its function through glutamate-gated chloride channels and GABA(A) receptors predominantly. There is paucity of information on anti-seizure activity of IVM. Moreover, the probable pharmacological mechanisms underlying this pheno...

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Autores principales:	Manavi, Mohammad Amin, Mohammad Jafari, Razieh, Shafaroodi, Hamed, Ejtemaei-Mehr, Shahram, Sharifzadeh, Mohammad, Dehpour, Ahmad Reza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647207/ https://www.ncbi.nlm.nih.gov/pubmed/36387449 http://dx.doi.org/10.1016/j.heliyon.2022.e11375

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