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Age/BMI is a Stronger Predictor of Death in COVID-19 Patients than Age Alone: A Pilot Study
The objective of this study was to investigate the effect of age and BMI on the risk of death in patients with coronavirus disease 2019 (COVID-19). A cohort of 206 Saudi COVID-19 patients was included in this study. Data on age, BMI, hospitalization, comorbidities, and death were collected and analy...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647239/ https://www.ncbi.nlm.nih.gov/pubmed/36355277 http://dx.doi.org/10.1007/s44197-022-00075-z |
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author | Al Balwi, Wala Al Turki, Maha Memish, Ziad A. Fakhoury, Hana M. A. Al Balwi, Mohammed Hajeer, Ali H. |
author_facet | Al Balwi, Wala Al Turki, Maha Memish, Ziad A. Fakhoury, Hana M. A. Al Balwi, Mohammed Hajeer, Ali H. |
author_sort | Al Balwi, Wala |
collection | PubMed |
description | The objective of this study was to investigate the effect of age and BMI on the risk of death in patients with coronavirus disease 2019 (COVID-19). A cohort of 206 Saudi COVID-19 patients was included in this study. Data on age, BMI, hospitalization, comorbidities, and death were collected and analyzed. Descriptive, univariate, and multivariate logistic regression analyses were carried out. Out of the 206 studied patients, 28 died. Hypertension, cardiac disease, and hospital admission were predictors of death in univariate and multivariate logistic regression analysis. Moreover, age was a significant predictor of death, while increased BMI seemed to be protective at an older age. Therefore, a new score was suggested taking into consideration both factors, namely age/BMI score. Although older age was associated with death in univariate (OR, 1.09 [95% CI 1.05–1.12], p < 0.001) and multivariate analysis (OR, 1.05 [95% CI 1.02–1.09], p = 0.004), a higher age/BMI score was a stronger predictor of death than age alone, in both univariate (OR 4.42 [95% CI 2.50–7.80], p < 0.001) and multivariate analysis (OR 3.11 [95% CI 1.66–5.82], p < 0.001). Several factors appear to contribute to the risk of COVID-19 death. Interestingly, our new age/BMI score seems to carry a higher risk of death than age alone. This new score will be designated as the Hajeer score. Since this is a small cohort study, we recommend investigating this score in a larger cohort. |
format | Online Article Text |
id | pubmed-9647239 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Springer Netherlands |
record_format | MEDLINE/PubMed |
spelling | pubmed-96472392022-11-14 Age/BMI is a Stronger Predictor of Death in COVID-19 Patients than Age Alone: A Pilot Study Al Balwi, Wala Al Turki, Maha Memish, Ziad A. Fakhoury, Hana M. A. Al Balwi, Mohammed Hajeer, Ali H. J Epidemiol Glob Health Research Article The objective of this study was to investigate the effect of age and BMI on the risk of death in patients with coronavirus disease 2019 (COVID-19). A cohort of 206 Saudi COVID-19 patients was included in this study. Data on age, BMI, hospitalization, comorbidities, and death were collected and analyzed. Descriptive, univariate, and multivariate logistic regression analyses were carried out. Out of the 206 studied patients, 28 died. Hypertension, cardiac disease, and hospital admission were predictors of death in univariate and multivariate logistic regression analysis. Moreover, age was a significant predictor of death, while increased BMI seemed to be protective at an older age. Therefore, a new score was suggested taking into consideration both factors, namely age/BMI score. Although older age was associated with death in univariate (OR, 1.09 [95% CI 1.05–1.12], p < 0.001) and multivariate analysis (OR, 1.05 [95% CI 1.02–1.09], p = 0.004), a higher age/BMI score was a stronger predictor of death than age alone, in both univariate (OR 4.42 [95% CI 2.50–7.80], p < 0.001) and multivariate analysis (OR 3.11 [95% CI 1.66–5.82], p < 0.001). Several factors appear to contribute to the risk of COVID-19 death. Interestingly, our new age/BMI score seems to carry a higher risk of death than age alone. This new score will be designated as the Hajeer score. Since this is a small cohort study, we recommend investigating this score in a larger cohort. Springer Netherlands 2022-11-10 /pmc/articles/PMC9647239/ /pubmed/36355277 http://dx.doi.org/10.1007/s44197-022-00075-z Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Research Article Al Balwi, Wala Al Turki, Maha Memish, Ziad A. Fakhoury, Hana M. A. Al Balwi, Mohammed Hajeer, Ali H. Age/BMI is a Stronger Predictor of Death in COVID-19 Patients than Age Alone: A Pilot Study |
title | Age/BMI is a Stronger Predictor of Death in COVID-19 Patients than Age Alone: A Pilot Study |
title_full | Age/BMI is a Stronger Predictor of Death in COVID-19 Patients than Age Alone: A Pilot Study |
title_fullStr | Age/BMI is a Stronger Predictor of Death in COVID-19 Patients than Age Alone: A Pilot Study |
title_full_unstemmed | Age/BMI is a Stronger Predictor of Death in COVID-19 Patients than Age Alone: A Pilot Study |
title_short | Age/BMI is a Stronger Predictor of Death in COVID-19 Patients than Age Alone: A Pilot Study |
title_sort | age/bmi is a stronger predictor of death in covid-19 patients than age alone: a pilot study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647239/ https://www.ncbi.nlm.nih.gov/pubmed/36355277 http://dx.doi.org/10.1007/s44197-022-00075-z |
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