Evolution of focal choroidal excavation in ABCA4-related retinopathy

PURPOSE: To report long-term evolution of unilateral focal choroidal excavation in a patient with ABCA4-related retinopathy. OBSERVATIONS: A 51-year-old female with ABCA4-related retinopathy developed a small juxtafoveal defect in Bruch's membrane in a region of macular atrophy in her left eye....

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Detalles Bibliográficos
Autores principales: Benson, Matthew D., Feldman, Carly B., Zein, Wadih M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647336/
https://www.ncbi.nlm.nih.gov/pubmed/36393906
http://dx.doi.org/10.1016/j.ajoc.2022.101740
Descripción
Sumario:PURPOSE: To report long-term evolution of unilateral focal choroidal excavation in a patient with ABCA4-related retinopathy. OBSERVATIONS: A 51-year-old female with ABCA4-related retinopathy developed a small juxtafoveal defect in Bruch's membrane in a region of macular atrophy in her left eye. In follow-up, the defect widened and subsequently developed into a focal choroidal excavation. Over the next 8 years, serial optical coherence tomography imaging illustrated the conversion of the focal choroidal excavation from conforming subtype into non-conforming subtype with eventual macular hole formation. CONCLUSIONS AND IMPORTANCE: The long-term follow-up of a patient with serial imaging highlights the potential dynamic nature of focal choroidal excavation in ABCA4-related retinopathy. Progressive retinal degeneration may influence focal choroidal excavation morphology and may promote macular hole formation.

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