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Didang Tang inhibits intracerebral hemorrhage-induced neuronal injury via ASK1/MKK7/JNK signaling pathway, network pharmacology-based analyses combined with experimental validation
BACKGROUND: Intracerebral hemorrhage (ICH) is an acute cerebrovascular disease, which is also a principal consideration for disability. Didang tang (DDT) is a classic traditional Chinese medicine formula for treating ICH. However, its pharmacological mechanism of action has not been elucidated. MATE...
Autores principales: | Lu, Jing, Tang, Xiaolei, Zhang, Dongmei, Lan, Tianye, Huang, Qingxia, Xu, Peng, Liu, Miao, Liu, Li, Wang, Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647469/ https://www.ncbi.nlm.nih.gov/pubmed/36387497 http://dx.doi.org/10.1016/j.heliyon.2022.e11407 |
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