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Impairment of peripheral nerve regeneration by insufficient activation of the HGF/c-Met/c-Jun pathway in aged mice

Aging in the peripheral nervous system (PNS) leads to its dysfunction and lowers regenerative capacity after injury. Based on the pro-regenerative effect of hepatocyte growth factor (HGF) in injured peripheral nerves, we investigated whether this growth factor is involved in the age-related degenera...

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Detalles Bibliográficos
Autores principales: Lee, Nayeon, Kim, Sunyoung, Lee, Junghun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647475/
https://www.ncbi.nlm.nih.gov/pubmed/36387562
http://dx.doi.org/10.1016/j.heliyon.2022.e11411