MicroRNA-16 inhibits the TLR4/NF-κB pathway and maintains tight junction integrity in irritable bowel syndrome with diarrhea

Irritable bowel syndrome with diarrhea (IBS-D) is a chronic and relapsing inflammatory disorder in which pathogenesis has been shown to be in part the result of miRNA-mediated signaling. Here, we investigated the alleviatory role of miR-16 in IBS-D. First, we established an IBS-D mouse model using c...

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Detalles Bibliográficos
Autores principales: Xi, Meijuan, Zhao, Ping, Li, Fang, Bao, Han, Ding, Sijie, Ji, Lijiang, Yan, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647533/
https://www.ncbi.nlm.nih.gov/pubmed/36067883
http://dx.doi.org/10.1016/j.jbc.2022.102461

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