Gemdimethyl Peptide Nucleic Acids (α/β/γ-gdm-PNA): E/Z-Rotamers Influence the Selectivity in the Formation of Parallel/Antiparallel gdm-PNA:DNA/RNA Duplexes

[Image: see text] Peptide nucleic acids (PNAs) consist of an aminoethylglycine (aeg) backbone to which the nucleobases are linked through a tertiary amide group and bind to complementary DNA/RNA in a sequence-specific manner. The flexible aeg backbone has been the target for several chemical modific...

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Detalles Bibliográficos
Autores principales: Kulkarni, Pradnya, Datta, Dhrubajyoti, Ganesh, Krishna N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647847/
https://www.ncbi.nlm.nih.gov/pubmed/36385799
http://dx.doi.org/10.1021/acsomega.2c05873

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647847/
https://www.ncbi.nlm.nih.gov/pubmed/36385799
http://dx.doi.org/10.1021/acsomega.2c05873

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