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A global high-density chromatin interaction network reveals functional long-range and trans-chromosomal relationships
BACKGROUND: Chromatin contacts are essential for gene-expression regulation; however, obtaining a high-resolution genome-wide chromatin contact map is still prohibitively expensive owing to large genome sizes and the quadratic scale of pairwise data. Chromosome conformation capture (3C)-based method...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9647974/ https://www.ncbi.nlm.nih.gov/pubmed/36352464 http://dx.doi.org/10.1186/s13059-022-02790-z |