Cargando…

Croatian study on COVID-19-positive stroke patients during the second wave of the pandemic

AIM: To investigate stroke characteristics in patients with concomitant coronavirus disease 2019 (COVID-19) infection in Croatia during the second wave of the COVID-19 pandemic. METHODS: This retrospective study investigated the characteristics of two groups of ischemic stroke patients: those who de...

Descripción completa

Detalles Bibliográficos
Autores principales: Rutović, Stela, Sporiš, Davor, Crnjaković, Miljenko, Vukorepa, Gorana, Deveđija, Sabina, Malojčić, Branko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Croatian Medical Schools 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648083/
https://www.ncbi.nlm.nih.gov/pubmed/36325667
http://dx.doi.org/10.3325/cmj.2022.63.431
_version_ 1784827504832282624
author Rutović, Stela
Sporiš, Davor
Crnjaković, Miljenko
Vukorepa, Gorana
Deveđija, Sabina
Malojčić, Branko
author_facet Rutović, Stela
Sporiš, Davor
Crnjaković, Miljenko
Vukorepa, Gorana
Deveđija, Sabina
Malojčić, Branko
author_sort Rutović, Stela
collection PubMed
description AIM: To investigate stroke characteristics in patients with concomitant coronavirus disease 2019 (COVID-19) infection in Croatia during the second wave of the COVID-19 pandemic. METHODS: This retrospective study investigated the characteristics of two groups of ischemic stroke patients: those who developed COVID-19 infection before stroke and those who developed the infection during the hospital stay after stroke onset. Stroke etiology was classified according to the Trial of Org 10172 in Acute Stroke Treatment (TOAST) classification. RESULTS: We analyzed data from 255 stroke patients from 12 Croatian hospitals. The two groups of ischemic stroke patients differed in stroke etiology (P = 0.038). Patients with COVID-19 infection before stroke had fewer cardioembolic strokes (46% vs 29.1%), more cryptogenic strokes (32.5% vs 14.3%), and more strokes in multiple vascular territories (12.4% vs 1.8%). The percentage of large-vessel occlusions was high in both groups (49.6% and 44.4%). Median modified Rankin Scale score on discharge was 4 in both groups. Mortality was 36.4% in the group with stroke after COVID-19 and 33.3% in the group with COVID-19 after stroke. CONCLUSION: Ischemic stroke after COVID-19 differs in etiology from ischemic stroke complicated by COVID-19 infection. Both patient groups are characterized by severe disability and high mortality. Raising the awareness of prehospital stroke and optimization of clinical workflow are important if we want to improve the stroke outcomes by acute recanalization techniques.
format Online
Article
Text
id pubmed-9648083
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Croatian Medical Schools
record_format MEDLINE/PubMed
spelling pubmed-96480832022-11-21 Croatian study on COVID-19-positive stroke patients during the second wave of the pandemic Rutović, Stela Sporiš, Davor Crnjaković, Miljenko Vukorepa, Gorana Deveđija, Sabina Malojčić, Branko Croat Med J Research Article AIM: To investigate stroke characteristics in patients with concomitant coronavirus disease 2019 (COVID-19) infection in Croatia during the second wave of the COVID-19 pandemic. METHODS: This retrospective study investigated the characteristics of two groups of ischemic stroke patients: those who developed COVID-19 infection before stroke and those who developed the infection during the hospital stay after stroke onset. Stroke etiology was classified according to the Trial of Org 10172 in Acute Stroke Treatment (TOAST) classification. RESULTS: We analyzed data from 255 stroke patients from 12 Croatian hospitals. The two groups of ischemic stroke patients differed in stroke etiology (P = 0.038). Patients with COVID-19 infection before stroke had fewer cardioembolic strokes (46% vs 29.1%), more cryptogenic strokes (32.5% vs 14.3%), and more strokes in multiple vascular territories (12.4% vs 1.8%). The percentage of large-vessel occlusions was high in both groups (49.6% and 44.4%). Median modified Rankin Scale score on discharge was 4 in both groups. Mortality was 36.4% in the group with stroke after COVID-19 and 33.3% in the group with COVID-19 after stroke. CONCLUSION: Ischemic stroke after COVID-19 differs in etiology from ischemic stroke complicated by COVID-19 infection. Both patient groups are characterized by severe disability and high mortality. Raising the awareness of prehospital stroke and optimization of clinical workflow are important if we want to improve the stroke outcomes by acute recanalization techniques. Croatian Medical Schools 2022-10 /pmc/articles/PMC9648083/ /pubmed/36325667 http://dx.doi.org/10.3325/cmj.2022.63.431 Text en Copyright © 2022 by the Croatian Medical Journal. All rights reserved. https://creativecommons.org/licenses/by/2.5/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Rutović, Stela
Sporiš, Davor
Crnjaković, Miljenko
Vukorepa, Gorana
Deveđija, Sabina
Malojčić, Branko
Croatian study on COVID-19-positive stroke patients during the second wave of the pandemic
title Croatian study on COVID-19-positive stroke patients during the second wave of the pandemic
title_full Croatian study on COVID-19-positive stroke patients during the second wave of the pandemic
title_fullStr Croatian study on COVID-19-positive stroke patients during the second wave of the pandemic
title_full_unstemmed Croatian study on COVID-19-positive stroke patients during the second wave of the pandemic
title_short Croatian study on COVID-19-positive stroke patients during the second wave of the pandemic
title_sort croatian study on covid-19-positive stroke patients during the second wave of the pandemic
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648083/
https://www.ncbi.nlm.nih.gov/pubmed/36325667
http://dx.doi.org/10.3325/cmj.2022.63.431
work_keys_str_mv AT rutovicstela croatianstudyoncovid19positivestrokepatientsduringthesecondwaveofthepandemic
AT sporisdavor croatianstudyoncovid19positivestrokepatientsduringthesecondwaveofthepandemic
AT crnjakovicmiljenko croatianstudyoncovid19positivestrokepatientsduringthesecondwaveofthepandemic
AT vukorepagorana croatianstudyoncovid19positivestrokepatientsduringthesecondwaveofthepandemic
AT deveđijasabina croatianstudyoncovid19positivestrokepatientsduringthesecondwaveofthepandemic
AT malojcicbranko croatianstudyoncovid19positivestrokepatientsduringthesecondwaveofthepandemic