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The clinical significance of allergen-specific IgG4 in allergic diseases

IgG4 is a subclass of IgG antibody with a unique molecular feature of (Fragment antigen- binding) Fab-arm exchange, allowing bispecific antigen binding in a mono-valent manner. With low binding affinity to C1q and Fcγreceptors, IgG4 is incapable of forming immune complexes and activating the complem...

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Detalles Bibliográficos
Autores principales:	Qin, Lu, Tang, Lan-Fang, Cheng, Lei, Wang, Hui-Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648126/ https://www.ncbi.nlm.nih.gov/pubmed/36389804 http://dx.doi.org/10.3389/fimmu.2022.1032909

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