ATRA-induced bradycardia in a case of acute promyelocytic leukemia: A case report

A 45-year-old female, a new case of acute promyelocytic leukemia (APL), received induction chemotherapy containing all-trans retinoic acid (ATRA) and idarubicin. On the sixth day of therapy, she developed sinus bradycardia and differentiation syndrome (DS). Electrolytes and cardiac imaging were norm...

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Autores principales: Rathod, Santosh Govind, Khan, Afaq Ahmad, Geelani, Sajad Ahmed, Roshan, Reshma, Bhat, Javid Rasool
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648224/
https://www.ncbi.nlm.nih.gov/pubmed/36387725
http://dx.doi.org/10.4103/jfmpc.jfmpc_1663_21
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author Rathod, Santosh Govind
Khan, Afaq Ahmad
Geelani, Sajad Ahmed
Roshan, Reshma
Bhat, Javid Rasool
author_facet Rathod, Santosh Govind
Khan, Afaq Ahmad
Geelani, Sajad Ahmed
Roshan, Reshma
Bhat, Javid Rasool
author_sort Rathod, Santosh Govind
collection PubMed
description A 45-year-old female, a new case of acute promyelocytic leukemia (APL), received induction chemotherapy containing all-trans retinoic acid (ATRA) and idarubicin. On the sixth day of therapy, she developed sinus bradycardia and differentiation syndrome (DS). Electrolytes and cardiac imaging were normal. The patient achieved normal sinus rhythm after ATRA was withheld, and DS was treated.
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spelling pubmed-96482242022-11-15 ATRA-induced bradycardia in a case of acute promyelocytic leukemia: A case report Rathod, Santosh Govind Khan, Afaq Ahmad Geelani, Sajad Ahmed Roshan, Reshma Bhat, Javid Rasool J Family Med Prim Care Case Report A 45-year-old female, a new case of acute promyelocytic leukemia (APL), received induction chemotherapy containing all-trans retinoic acid (ATRA) and idarubicin. On the sixth day of therapy, she developed sinus bradycardia and differentiation syndrome (DS). Electrolytes and cardiac imaging were normal. The patient achieved normal sinus rhythm after ATRA was withheld, and DS was treated. Wolters Kluwer - Medknow 2022-07 2022-07-22 /pmc/articles/PMC9648224/ /pubmed/36387725 http://dx.doi.org/10.4103/jfmpc.jfmpc_1663_21 Text en Copyright: © 2022 Journal of Family Medicine and Primary Care https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Rathod, Santosh Govind
Khan, Afaq Ahmad
Geelani, Sajad Ahmed
Roshan, Reshma
Bhat, Javid Rasool
ATRA-induced bradycardia in a case of acute promyelocytic leukemia: A case report
title ATRA-induced bradycardia in a case of acute promyelocytic leukemia: A case report
title_full ATRA-induced bradycardia in a case of acute promyelocytic leukemia: A case report
title_fullStr ATRA-induced bradycardia in a case of acute promyelocytic leukemia: A case report
title_full_unstemmed ATRA-induced bradycardia in a case of acute promyelocytic leukemia: A case report
title_short ATRA-induced bradycardia in a case of acute promyelocytic leukemia: A case report
title_sort atra-induced bradycardia in a case of acute promyelocytic leukemia: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648224/
https://www.ncbi.nlm.nih.gov/pubmed/36387725
http://dx.doi.org/10.4103/jfmpc.jfmpc_1663_21
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