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Zinc oxide nanoparticles and spironolactone-enhanced Nrf2/HO-1 pathway and inhibited Wnt/β-catenin pathway in adenine-induced nephrotoxicity in rats

OBJECTIVE: To investigate the renoprotective, the antioxidant, and the anti-inflammatory impact of a combination of SPL and ZnO-NPs to combat against chronic kidney disease (CKD). METHODS: In total, 50 males of rats were distributed into 5 groups (10 rats each); normal group, adenine sulfate (0.25%...

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Detalles Bibliográficos
Autores principales:	Awadalla, Amira, Hamam, Eman T., El-Senduny, Fardous F., Omar, Nisreen Mansour, Mahdi, Mohamed R., Barakat, Nashwa, Ammar, Omar A., Hussein, Abdelaziz M., Shokeir, Ahmed A., Khirallah, Salma M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648381/ https://www.ncbi.nlm.nih.gov/pubmed/36342062 http://dx.doi.org/10.1080/13510002.2022.2139947

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