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Hospital Admissions Secondary to Diseases of the Blood, Blood-Forming Organs, and Immune System in England and Wales

Background Non-malignant hematologic and immune disorders-related hospitalization trends are unstudied despite their importance from a public health standpoint. Therefore, this study aimed to define the hospitalization trends of the International Statistical Classification of Diseases-10 (ICD-10) ca...

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Autores principales: Mustafa Ali, Moaath K, Naser, Abdallah Y, AbuAlhommos, Amal, Al-Daghastani, Tamara, Alrawashdeh, Hamzeh, Mustafa Ali, Saja, Alwafi, Hassan, Alqurashi, Mohammed Mansour, Basha Ahmed, Abdulaziz H, Albarqi, Hussein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648385/
https://www.ncbi.nlm.nih.gov/pubmed/36397897
http://dx.doi.org/10.7759/cureus.30179
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author Mustafa Ali, Moaath K
Naser, Abdallah Y
AbuAlhommos, Amal
Al-Daghastani, Tamara
Alrawashdeh, Hamzeh
Mustafa Ali, Saja
Alwafi, Hassan
Alqurashi, Mohammed Mansour
Basha Ahmed, Abdulaziz H
Albarqi, Hussein
author_facet Mustafa Ali, Moaath K
Naser, Abdallah Y
AbuAlhommos, Amal
Al-Daghastani, Tamara
Alrawashdeh, Hamzeh
Mustafa Ali, Saja
Alwafi, Hassan
Alqurashi, Mohammed Mansour
Basha Ahmed, Abdulaziz H
Albarqi, Hussein
author_sort Mustafa Ali, Moaath K
collection PubMed
description Background Non-malignant hematologic and immune disorders-related hospitalization trends are unstudied despite their importance from a public health standpoint. Therefore, this study aimed to define the hospitalization trends of the International Statistical Classification of Diseases-10 (ICD-10) category diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (B&ID). Methods We conducted an ecologic study to analyze hospital admission data obtained from England's Hospital Episode Statistics database and Wales' Patient Episode Database. Hospital admissions data for non-malignant hematologic disorders and immune disorders were extracted for the period from April 1999 to March 2019. We used the Poisson model to assess trends in hospital admissions. Results The total annual B&ID-related hospital admission (RHA) rate for all categories increased by 137.9% between 1999 and 2019 (p<0.01). Females accounted for 54% of all B&ID-RHA. Around 37% of B&ID-RHA were seen in the age group of 15-59 years and 29% in the age group of 75 years and above. The most common causes of B&ID-RHA were aplastic and other anemias and other bone marrow failure syndromes, ICD-10 category (33%) and nutritional anemias category (28%). Certain disorders involving the immune mechanism category accounted for the least number of B&ID-RHA (8.4%). The highest increase in B&ID-RHA was seen in the nutritional anemias category (3.86 fold), followed by certain disorders involving the immune mechanism (1.28 fold). Iron deficiency anemia accounted for 95.1% of all hospitalizations secondary to nutritional anemias. Around half of all, hemolytic anemia category hospitalizations were secondary to the sickle cell anemia subcategory. Conclusions Hospital admissions trends in non-malignant hematologic and immune disorders changed dynamically among age groups and gender in England and Wales over the last two decades. Understanding these changes has important implications for public health planning.
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spelling pubmed-96483852022-11-16 Hospital Admissions Secondary to Diseases of the Blood, Blood-Forming Organs, and Immune System in England and Wales Mustafa Ali, Moaath K Naser, Abdallah Y AbuAlhommos, Amal Al-Daghastani, Tamara Alrawashdeh, Hamzeh Mustafa Ali, Saja Alwafi, Hassan Alqurashi, Mohammed Mansour Basha Ahmed, Abdulaziz H Albarqi, Hussein Cureus Epidemiology/Public Health Background Non-malignant hematologic and immune disorders-related hospitalization trends are unstudied despite their importance from a public health standpoint. Therefore, this study aimed to define the hospitalization trends of the International Statistical Classification of Diseases-10 (ICD-10) category diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (B&ID). Methods We conducted an ecologic study to analyze hospital admission data obtained from England's Hospital Episode Statistics database and Wales' Patient Episode Database. Hospital admissions data for non-malignant hematologic disorders and immune disorders were extracted for the period from April 1999 to March 2019. We used the Poisson model to assess trends in hospital admissions. Results The total annual B&ID-related hospital admission (RHA) rate for all categories increased by 137.9% between 1999 and 2019 (p<0.01). Females accounted for 54% of all B&ID-RHA. Around 37% of B&ID-RHA were seen in the age group of 15-59 years and 29% in the age group of 75 years and above. The most common causes of B&ID-RHA were aplastic and other anemias and other bone marrow failure syndromes, ICD-10 category (33%) and nutritional anemias category (28%). Certain disorders involving the immune mechanism category accounted for the least number of B&ID-RHA (8.4%). The highest increase in B&ID-RHA was seen in the nutritional anemias category (3.86 fold), followed by certain disorders involving the immune mechanism (1.28 fold). Iron deficiency anemia accounted for 95.1% of all hospitalizations secondary to nutritional anemias. Around half of all, hemolytic anemia category hospitalizations were secondary to the sickle cell anemia subcategory. Conclusions Hospital admissions trends in non-malignant hematologic and immune disorders changed dynamically among age groups and gender in England and Wales over the last two decades. Understanding these changes has important implications for public health planning. Cureus 2022-10-11 /pmc/articles/PMC9648385/ /pubmed/36397897 http://dx.doi.org/10.7759/cureus.30179 Text en Copyright © 2022, Mustafa Ali et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Epidemiology/Public Health
Mustafa Ali, Moaath K
Naser, Abdallah Y
AbuAlhommos, Amal
Al-Daghastani, Tamara
Alrawashdeh, Hamzeh
Mustafa Ali, Saja
Alwafi, Hassan
Alqurashi, Mohammed Mansour
Basha Ahmed, Abdulaziz H
Albarqi, Hussein
Hospital Admissions Secondary to Diseases of the Blood, Blood-Forming Organs, and Immune System in England and Wales
title Hospital Admissions Secondary to Diseases of the Blood, Blood-Forming Organs, and Immune System in England and Wales
title_full Hospital Admissions Secondary to Diseases of the Blood, Blood-Forming Organs, and Immune System in England and Wales
title_fullStr Hospital Admissions Secondary to Diseases of the Blood, Blood-Forming Organs, and Immune System in England and Wales
title_full_unstemmed Hospital Admissions Secondary to Diseases of the Blood, Blood-Forming Organs, and Immune System in England and Wales
title_short Hospital Admissions Secondary to Diseases of the Blood, Blood-Forming Organs, and Immune System in England and Wales
title_sort hospital admissions secondary to diseases of the blood, blood-forming organs, and immune system in england and wales
topic Epidemiology/Public Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648385/
https://www.ncbi.nlm.nih.gov/pubmed/36397897
http://dx.doi.org/10.7759/cureus.30179
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