Cargando…
Hospital Admissions Secondary to Diseases of the Blood, Blood-Forming Organs, and Immune System in England and Wales
Background Non-malignant hematologic and immune disorders-related hospitalization trends are unstudied despite their importance from a public health standpoint. Therefore, this study aimed to define the hospitalization trends of the International Statistical Classification of Diseases-10 (ICD-10) ca...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648385/ https://www.ncbi.nlm.nih.gov/pubmed/36397897 http://dx.doi.org/10.7759/cureus.30179 |
_version_ | 1784827575290298368 |
---|---|
author | Mustafa Ali, Moaath K Naser, Abdallah Y AbuAlhommos, Amal Al-Daghastani, Tamara Alrawashdeh, Hamzeh Mustafa Ali, Saja Alwafi, Hassan Alqurashi, Mohammed Mansour Basha Ahmed, Abdulaziz H Albarqi, Hussein |
author_facet | Mustafa Ali, Moaath K Naser, Abdallah Y AbuAlhommos, Amal Al-Daghastani, Tamara Alrawashdeh, Hamzeh Mustafa Ali, Saja Alwafi, Hassan Alqurashi, Mohammed Mansour Basha Ahmed, Abdulaziz H Albarqi, Hussein |
author_sort | Mustafa Ali, Moaath K |
collection | PubMed |
description | Background Non-malignant hematologic and immune disorders-related hospitalization trends are unstudied despite their importance from a public health standpoint. Therefore, this study aimed to define the hospitalization trends of the International Statistical Classification of Diseases-10 (ICD-10) category diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (B&ID). Methods We conducted an ecologic study to analyze hospital admission data obtained from England's Hospital Episode Statistics database and Wales' Patient Episode Database. Hospital admissions data for non-malignant hematologic disorders and immune disorders were extracted for the period from April 1999 to March 2019. We used the Poisson model to assess trends in hospital admissions. Results The total annual B&ID-related hospital admission (RHA) rate for all categories increased by 137.9% between 1999 and 2019 (p<0.01). Females accounted for 54% of all B&ID-RHA. Around 37% of B&ID-RHA were seen in the age group of 15-59 years and 29% in the age group of 75 years and above. The most common causes of B&ID-RHA were aplastic and other anemias and other bone marrow failure syndromes, ICD-10 category (33%) and nutritional anemias category (28%). Certain disorders involving the immune mechanism category accounted for the least number of B&ID-RHA (8.4%). The highest increase in B&ID-RHA was seen in the nutritional anemias category (3.86 fold), followed by certain disorders involving the immune mechanism (1.28 fold). Iron deficiency anemia accounted for 95.1% of all hospitalizations secondary to nutritional anemias. Around half of all, hemolytic anemia category hospitalizations were secondary to the sickle cell anemia subcategory. Conclusions Hospital admissions trends in non-malignant hematologic and immune disorders changed dynamically among age groups and gender in England and Wales over the last two decades. Understanding these changes has important implications for public health planning. |
format | Online Article Text |
id | pubmed-9648385 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-96483852022-11-16 Hospital Admissions Secondary to Diseases of the Blood, Blood-Forming Organs, and Immune System in England and Wales Mustafa Ali, Moaath K Naser, Abdallah Y AbuAlhommos, Amal Al-Daghastani, Tamara Alrawashdeh, Hamzeh Mustafa Ali, Saja Alwafi, Hassan Alqurashi, Mohammed Mansour Basha Ahmed, Abdulaziz H Albarqi, Hussein Cureus Epidemiology/Public Health Background Non-malignant hematologic and immune disorders-related hospitalization trends are unstudied despite their importance from a public health standpoint. Therefore, this study aimed to define the hospitalization trends of the International Statistical Classification of Diseases-10 (ICD-10) category diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism (B&ID). Methods We conducted an ecologic study to analyze hospital admission data obtained from England's Hospital Episode Statistics database and Wales' Patient Episode Database. Hospital admissions data for non-malignant hematologic disorders and immune disorders were extracted for the period from April 1999 to March 2019. We used the Poisson model to assess trends in hospital admissions. Results The total annual B&ID-related hospital admission (RHA) rate for all categories increased by 137.9% between 1999 and 2019 (p<0.01). Females accounted for 54% of all B&ID-RHA. Around 37% of B&ID-RHA were seen in the age group of 15-59 years and 29% in the age group of 75 years and above. The most common causes of B&ID-RHA were aplastic and other anemias and other bone marrow failure syndromes, ICD-10 category (33%) and nutritional anemias category (28%). Certain disorders involving the immune mechanism category accounted for the least number of B&ID-RHA (8.4%). The highest increase in B&ID-RHA was seen in the nutritional anemias category (3.86 fold), followed by certain disorders involving the immune mechanism (1.28 fold). Iron deficiency anemia accounted for 95.1% of all hospitalizations secondary to nutritional anemias. Around half of all, hemolytic anemia category hospitalizations were secondary to the sickle cell anemia subcategory. Conclusions Hospital admissions trends in non-malignant hematologic and immune disorders changed dynamically among age groups and gender in England and Wales over the last two decades. Understanding these changes has important implications for public health planning. Cureus 2022-10-11 /pmc/articles/PMC9648385/ /pubmed/36397897 http://dx.doi.org/10.7759/cureus.30179 Text en Copyright © 2022, Mustafa Ali et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Epidemiology/Public Health Mustafa Ali, Moaath K Naser, Abdallah Y AbuAlhommos, Amal Al-Daghastani, Tamara Alrawashdeh, Hamzeh Mustafa Ali, Saja Alwafi, Hassan Alqurashi, Mohammed Mansour Basha Ahmed, Abdulaziz H Albarqi, Hussein Hospital Admissions Secondary to Diseases of the Blood, Blood-Forming Organs, and Immune System in England and Wales |
title | Hospital Admissions Secondary to Diseases of the Blood, Blood-Forming Organs, and Immune System in England and Wales |
title_full | Hospital Admissions Secondary to Diseases of the Blood, Blood-Forming Organs, and Immune System in England and Wales |
title_fullStr | Hospital Admissions Secondary to Diseases of the Blood, Blood-Forming Organs, and Immune System in England and Wales |
title_full_unstemmed | Hospital Admissions Secondary to Diseases of the Blood, Blood-Forming Organs, and Immune System in England and Wales |
title_short | Hospital Admissions Secondary to Diseases of the Blood, Blood-Forming Organs, and Immune System in England and Wales |
title_sort | hospital admissions secondary to diseases of the blood, blood-forming organs, and immune system in england and wales |
topic | Epidemiology/Public Health |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648385/ https://www.ncbi.nlm.nih.gov/pubmed/36397897 http://dx.doi.org/10.7759/cureus.30179 |
work_keys_str_mv | AT mustafaalimoaathk hospitaladmissionssecondarytodiseasesofthebloodbloodformingorgansandimmunesysteminenglandandwales AT naserabdallahy hospitaladmissionssecondarytodiseasesofthebloodbloodformingorgansandimmunesysteminenglandandwales AT abualhommosamal hospitaladmissionssecondarytodiseasesofthebloodbloodformingorgansandimmunesysteminenglandandwales AT aldaghastanitamara hospitaladmissionssecondarytodiseasesofthebloodbloodformingorgansandimmunesysteminenglandandwales AT alrawashdehhamzeh hospitaladmissionssecondarytodiseasesofthebloodbloodformingorgansandimmunesysteminenglandandwales AT mustafaalisaja hospitaladmissionssecondarytodiseasesofthebloodbloodformingorgansandimmunesysteminenglandandwales AT alwafihassan hospitaladmissionssecondarytodiseasesofthebloodbloodformingorgansandimmunesysteminenglandandwales AT alqurashimohammedmansour hospitaladmissionssecondarytodiseasesofthebloodbloodformingorgansandimmunesysteminenglandandwales AT bashaahmedabdulazizh hospitaladmissionssecondarytodiseasesofthebloodbloodformingorgansandimmunesysteminenglandandwales AT albarqihussein hospitaladmissionssecondarytodiseasesofthebloodbloodformingorgansandimmunesysteminenglandandwales |