A novel strategy for orthogonal genetic regulation on different RNA targeted loci simultaneously

No current RNA-targeted interference tools have been reported to simultaneously up and down-regulate different gene expressions. Here we characterized an RNA-targeted genetic regulatory strategy composed of a flap endonuclease 1 (FEN1) and specific mis-hairpin DNA probes (mis-hpDNA), to realize the...

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Detalles Bibliográficos
Autores principales: Guo, Yongjian, Wang, Liang, Qi, Zhen, Liu, Yu, Tian, Kun, Qiang, Huanran, Wang, Pei, Zhou, Guohua, Zhang, Xiaobo, Xu, Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648401/
https://www.ncbi.nlm.nih.gov/pubmed/36350790
http://dx.doi.org/10.1080/15476286.2022.2141507

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