Post-Transfusion Simultaneous Thrombotic Thrombocytopenic Purpura and Hemolytic Uremic Syndrome: A Rare Occurrence

Endothelial cell injury, intravascular platelet-fibrin thrombi, and vascular damage are found in hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP). The two disorders frequently manifest independently and are the important causes of acute renal damage. Acute kidney injury...

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Autores principales: Patel, Maharshi, Pawar, Twinkle, Agrawal, Sachin, Mudey, Gargi, Kumar, Sunil, Acharya, Sourya, Manuja, Nishtha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648416/
https://www.ncbi.nlm.nih.gov/pubmed/36397896
http://dx.doi.org/10.7759/cureus.30181
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author Patel, Maharshi
Pawar, Twinkle
Agrawal, Sachin
Mudey, Gargi
Kumar, Sunil
Acharya, Sourya
Manuja, Nishtha
author_facet Patel, Maharshi
Pawar, Twinkle
Agrawal, Sachin
Mudey, Gargi
Kumar, Sunil
Acharya, Sourya
Manuja, Nishtha
author_sort Patel, Maharshi
collection PubMed
description Endothelial cell injury, intravascular platelet-fibrin thrombi, and vascular damage are found in hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP). The two disorders frequently manifest independently and are the important causes of acute renal damage. Acute kidney injury developed in our patient after blood transfusion and later on, the patient developed neurological complications. The patient was managed symptomatically and conservatively. Plasmapheresis and corticosteroid administration showed improved results.
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spelling pubmed-96484162022-11-16 Post-Transfusion Simultaneous Thrombotic Thrombocytopenic Purpura and Hemolytic Uremic Syndrome: A Rare Occurrence Patel, Maharshi Pawar, Twinkle Agrawal, Sachin Mudey, Gargi Kumar, Sunil Acharya, Sourya Manuja, Nishtha Cureus Internal Medicine Endothelial cell injury, intravascular platelet-fibrin thrombi, and vascular damage are found in hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP). The two disorders frequently manifest independently and are the important causes of acute renal damage. Acute kidney injury developed in our patient after blood transfusion and later on, the patient developed neurological complications. The patient was managed symptomatically and conservatively. Plasmapheresis and corticosteroid administration showed improved results. Cureus 2022-10-11 /pmc/articles/PMC9648416/ /pubmed/36397896 http://dx.doi.org/10.7759/cureus.30181 Text en Copyright © 2022, Patel et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Patel, Maharshi
Pawar, Twinkle
Agrawal, Sachin
Mudey, Gargi
Kumar, Sunil
Acharya, Sourya
Manuja, Nishtha
Post-Transfusion Simultaneous Thrombotic Thrombocytopenic Purpura and Hemolytic Uremic Syndrome: A Rare Occurrence
title Post-Transfusion Simultaneous Thrombotic Thrombocytopenic Purpura and Hemolytic Uremic Syndrome: A Rare Occurrence
title_full Post-Transfusion Simultaneous Thrombotic Thrombocytopenic Purpura and Hemolytic Uremic Syndrome: A Rare Occurrence
title_fullStr Post-Transfusion Simultaneous Thrombotic Thrombocytopenic Purpura and Hemolytic Uremic Syndrome: A Rare Occurrence
title_full_unstemmed Post-Transfusion Simultaneous Thrombotic Thrombocytopenic Purpura and Hemolytic Uremic Syndrome: A Rare Occurrence
title_short Post-Transfusion Simultaneous Thrombotic Thrombocytopenic Purpura and Hemolytic Uremic Syndrome: A Rare Occurrence
title_sort post-transfusion simultaneous thrombotic thrombocytopenic purpura and hemolytic uremic syndrome: a rare occurrence
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648416/
https://www.ncbi.nlm.nih.gov/pubmed/36397896
http://dx.doi.org/10.7759/cureus.30181
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