A variant-proof SARS-CoV-2 vaccine targeting HR1 domain in S2 subunit of spike protein

The emerging SARS-CoV-2 variants, commonly with many mutations in S1 subunit of spike (S) protein are weakening the efficacy of the current vaccines and antibody therapeutics. This calls for the variant-proof SARS-CoV-2 vaccines targeting the more conserved regions in S protein. Here, we designed a...

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Detalles Bibliográficos
Autores principales: Pang, Wei, Lu, Ying, Zhao, Yan-Bo, Shen, Fan, Fan, Chang-Fa, Wang, Qian, He, Wen-Qiang, He, Xiao-Yan, Li, Ze-Kai, Chen, Tao-Tao, Yang, Cui-Xian, Li, You-Zhi, Xiao, Si-Xuan, Zhao, Zu-Jiang, Huang, Xu-Sheng, Luo, Rong-Hua, Yang, Liu-Meng, Zhang, Mi, Dong, Xing-Qi, Li, Ming-Hua, Feng, Xiao-Li, Zhou, Qing-Cui, Qu, Wang, Jiang, Shibo, Ouyang, Songying, Zheng, Yong-Tang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648449/
https://www.ncbi.nlm.nih.gov/pubmed/36357786
http://dx.doi.org/10.1038/s41422-022-00746-3

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