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Evaluation and Management of Nonsyndromic Craniosynostosis
Nonsyndromic craniosynostosis (NSC) is more common than syndromic craniosynostosis and predominantly involves single suture. It affects sagittal, coronal, metopic, and lambdoid sutures in the decreasing order of frequency. A surgery for NSC is generally recommended to avoid potential neurodevelopmen...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648650/ https://www.ncbi.nlm.nih.gov/pubmed/36388009 http://dx.doi.org/10.4103/jpn.JPN_17_22 |
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author | Marbate, Tushar Kedia, Shweta Gupta, Deepak K |
author_facet | Marbate, Tushar Kedia, Shweta Gupta, Deepak K |
author_sort | Marbate, Tushar |
collection | PubMed |
description | Nonsyndromic craniosynostosis (NSC) is more common than syndromic craniosynostosis and predominantly involves single suture. It affects sagittal, coronal, metopic, and lambdoid sutures in the decreasing order of frequency. A surgery for NSC is generally recommended to avoid potential neurodevelopmental delays and sequelae of raised intracranial pressure. Open calvarial vault reconstruction, strip craniectomy with/without the use of a postoperative molding helmet, strip craniectomy with spring implantations, endoscopic suture release, and cranial distraction osteogenesis are various surgical options used for NSC cases. The ideal age for intervention is 6–12 months for open procedures and 3–4 months for endoscopic approaches. The management is directed toward minimizing operative trauma and improving the neurocognitive outcome. The role of nonsurgical intervention by the use of genetic manipulation is still not a reality because of the nature of disease and time of presentation. |
format | Online Article Text |
id | pubmed-9648650 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-96486502022-11-15 Evaluation and Management of Nonsyndromic Craniosynostosis Marbate, Tushar Kedia, Shweta Gupta, Deepak K J Pediatr Neurosci Review Article Nonsyndromic craniosynostosis (NSC) is more common than syndromic craniosynostosis and predominantly involves single suture. It affects sagittal, coronal, metopic, and lambdoid sutures in the decreasing order of frequency. A surgery for NSC is generally recommended to avoid potential neurodevelopmental delays and sequelae of raised intracranial pressure. Open calvarial vault reconstruction, strip craniectomy with/without the use of a postoperative molding helmet, strip craniectomy with spring implantations, endoscopic suture release, and cranial distraction osteogenesis are various surgical options used for NSC cases. The ideal age for intervention is 6–12 months for open procedures and 3–4 months for endoscopic approaches. The management is directed toward minimizing operative trauma and improving the neurocognitive outcome. The role of nonsurgical intervention by the use of genetic manipulation is still not a reality because of the nature of disease and time of presentation. Wolters Kluwer - Medknow 2022-09 2022-09-19 /pmc/articles/PMC9648650/ /pubmed/36388009 http://dx.doi.org/10.4103/jpn.JPN_17_22 Text en Copyright: © 2022 Journal of Pediatric Neurosciences https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Review Article Marbate, Tushar Kedia, Shweta Gupta, Deepak K Evaluation and Management of Nonsyndromic Craniosynostosis |
title | Evaluation and Management of Nonsyndromic Craniosynostosis |
title_full | Evaluation and Management of Nonsyndromic Craniosynostosis |
title_fullStr | Evaluation and Management of Nonsyndromic Craniosynostosis |
title_full_unstemmed | Evaluation and Management of Nonsyndromic Craniosynostosis |
title_short | Evaluation and Management of Nonsyndromic Craniosynostosis |
title_sort | evaluation and management of nonsyndromic craniosynostosis |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648650/ https://www.ncbi.nlm.nih.gov/pubmed/36388009 http://dx.doi.org/10.4103/jpn.JPN_17_22 |
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