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Evaluation and Management of Nonsyndromic Craniosynostosis

Nonsyndromic craniosynostosis (NSC) is more common than syndromic craniosynostosis and predominantly involves single suture. It affects sagittal, coronal, metopic, and lambdoid sutures in the decreasing order of frequency. A surgery for NSC is generally recommended to avoid potential neurodevelopmen...

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Detalles Bibliográficos
Autores principales: Marbate, Tushar, Kedia, Shweta, Gupta, Deepak K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648650/
https://www.ncbi.nlm.nih.gov/pubmed/36388009
http://dx.doi.org/10.4103/jpn.JPN_17_22
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author Marbate, Tushar
Kedia, Shweta
Gupta, Deepak K
author_facet Marbate, Tushar
Kedia, Shweta
Gupta, Deepak K
author_sort Marbate, Tushar
collection PubMed
description Nonsyndromic craniosynostosis (NSC) is more common than syndromic craniosynostosis and predominantly involves single suture. It affects sagittal, coronal, metopic, and lambdoid sutures in the decreasing order of frequency. A surgery for NSC is generally recommended to avoid potential neurodevelopmental delays and sequelae of raised intracranial pressure. Open calvarial vault reconstruction, strip craniectomy with/without the use of a postoperative molding helmet, strip craniectomy with spring implantations, endoscopic suture release, and cranial distraction osteogenesis are various surgical options used for NSC cases. The ideal age for intervention is 6–12 months for open procedures and 3–4 months for endoscopic approaches. The management is directed toward minimizing operative trauma and improving the neurocognitive outcome. The role of nonsurgical intervention by the use of genetic manipulation is still not a reality because of the nature of disease and time of presentation.
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spelling pubmed-96486502022-11-15 Evaluation and Management of Nonsyndromic Craniosynostosis Marbate, Tushar Kedia, Shweta Gupta, Deepak K J Pediatr Neurosci Review Article Nonsyndromic craniosynostosis (NSC) is more common than syndromic craniosynostosis and predominantly involves single suture. It affects sagittal, coronal, metopic, and lambdoid sutures in the decreasing order of frequency. A surgery for NSC is generally recommended to avoid potential neurodevelopmental delays and sequelae of raised intracranial pressure. Open calvarial vault reconstruction, strip craniectomy with/without the use of a postoperative molding helmet, strip craniectomy with spring implantations, endoscopic suture release, and cranial distraction osteogenesis are various surgical options used for NSC cases. The ideal age for intervention is 6–12 months for open procedures and 3–4 months for endoscopic approaches. The management is directed toward minimizing operative trauma and improving the neurocognitive outcome. The role of nonsurgical intervention by the use of genetic manipulation is still not a reality because of the nature of disease and time of presentation. Wolters Kluwer - Medknow 2022-09 2022-09-19 /pmc/articles/PMC9648650/ /pubmed/36388009 http://dx.doi.org/10.4103/jpn.JPN_17_22 Text en Copyright: © 2022 Journal of Pediatric Neurosciences https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Review Article
Marbate, Tushar
Kedia, Shweta
Gupta, Deepak K
Evaluation and Management of Nonsyndromic Craniosynostosis
title Evaluation and Management of Nonsyndromic Craniosynostosis
title_full Evaluation and Management of Nonsyndromic Craniosynostosis
title_fullStr Evaluation and Management of Nonsyndromic Craniosynostosis
title_full_unstemmed Evaluation and Management of Nonsyndromic Craniosynostosis
title_short Evaluation and Management of Nonsyndromic Craniosynostosis
title_sort evaluation and management of nonsyndromic craniosynostosis
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648650/
https://www.ncbi.nlm.nih.gov/pubmed/36388009
http://dx.doi.org/10.4103/jpn.JPN_17_22
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