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Age-associated changes in microglia activation and Sirtuin-1- chromatin binding patterns

The aging process is associated with changes in mechanisms maintaining physiology, influenced by genetics and lifestyle, and impacting late life quality and longevity. Brain health is critical in healthy aging. Sirtuin 1 (Sirt1), a histone deacetylase with silencing properties, is one of the molecul...

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Detalles Bibliográficos
Autores principales: Basova, Liana V., Bortell, Nikki, Conti, Bruno, Fox, Howard S., Milner, Richard, Marcondes, Maria Cecilia Garibaldi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648798/
https://www.ncbi.nlm.nih.gov/pubmed/36227148
http://dx.doi.org/10.18632/aging.204329