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α-Synuclein upregulates bim-mediated apoptosis by negatively regulating endogenous GCN5
α-synuclein (αS) is a β-sheet intracellular protein that has been implicated as a major pathological hallmark of Parkinson’s disease (PD). Several studies have shown that overexpression of αS causes dopaminergic cell loss; however, the role of αS in apoptosis remains not fully known. Therefore, this...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Impact Journals
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648804/ https://www.ncbi.nlm.nih.gov/pubmed/36309909 http://dx.doi.org/10.18632/aging.204353 |