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NOX1 mediates metabolic heart disease in mice and is upregulated in monocytes of humans with diastolic dysfunction

AIMS: Microvascular inflammation plays an important role in the pathogenesis of diastolic dysfunction (DD) and metabolic heart disease. NOX1 is expressed in vascular and immune cells and has been implicated in the vascular pathology of metabolic disease. However, its contribution to metabolic heart...

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Detalles Bibliográficos
Autores principales:	Xu, Lifen, Balzarolo, Melania, Robinson, Emma L, Lorenz, Vera, Della Verde, Giacomo, Joray, Lydia, Mochizuki, Michika, Kaufmann, Beat A, Valstar, Gideon, de Jager, Saskia C A, den Ruijter, Hester M, Heymans, Stephane, Pfister, Otmar, Kuster, Gabriela M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648822/ https://www.ncbi.nlm.nih.gov/pubmed/34849611 http://dx.doi.org/10.1093/cvr/cvab349

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