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Free ISG15 inhibits Pseudorabies virus infection by positively regulating type I IFN signaling
Interferon-stimulated gene 15 (ISG15) is strongly upregulated during viral infections and exerts pro-viral or antiviral actions. While many viruses combat host antiviral defenses by limiting ISG expression, PRV infection notably increases expression of ISG15. However, studies on the viral strategies...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648840/ https://www.ncbi.nlm.nih.gov/pubmed/36315588 http://dx.doi.org/10.1371/journal.ppat.1010921 |