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Free ISG15 inhibits Pseudorabies virus infection by positively regulating type I IFN signaling

Interferon-stimulated gene 15 (ISG15) is strongly upregulated during viral infections and exerts pro-viral or antiviral actions. While many viruses combat host antiviral defenses by limiting ISG expression, PRV infection notably increases expression of ISG15. However, studies on the viral strategies...

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Detalles Bibliográficos
Autores principales:	Liu, Huimin, Li, Chen, He, Wenfeng, Chen, Jing, Yang, Guoqing, Chen, Lu, Chang, Hongtao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648840/ https://www.ncbi.nlm.nih.gov/pubmed/36315588 http://dx.doi.org/10.1371/journal.ppat.1010921

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