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Not all viruses cause disease: HERV-K(HML-2) in healthy human tissues

Human endogenous retroviruses (HERVs) make up a significant part of our genome. While their expression is frequently associated with disease, a new study in PLOS Biology found that HERV-K(HML-2) is expressed in more than 50 healthy tissues.

Detalles Bibliográficos
Autores principales: Srinivasachar Badarinarayan, Smitha, Sauter, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648852/
https://www.ncbi.nlm.nih.gov/pubmed/36315578
http://dx.doi.org/10.1371/journal.pbio.3001884
Descripción
Sumario:Human endogenous retroviruses (HERVs) make up a significant part of our genome. While their expression is frequently associated with disease, a new study in PLOS Biology found that HERV-K(HML-2) is expressed in more than 50 healthy tissues.