Cargando…

Differential requirements for mitochondrial electron transport chain components in the adult murine liver

Mitochondrial electron transport chain (ETC) dysfunction due to mutations in the nuclear or mitochondrial genome is a common cause of metabolic disease in humans and displays striking tissue specificity depending on the affected gene. The mechanisms underlying tissue-specific phenotypes are not unde...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lesner, Nicholas P, Wang, Xun, Chen, Zhenkang, Frank, Anderson, Menezes, Cameron J, House, Sara, Shelton, Spencer D, Lemoff, Andrew, McFadden, David G, Wansapura, Janaka, DeBerardinis, Ralph J, Mishra, Prashant
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2022
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9648974/ https://www.ncbi.nlm.nih.gov/pubmed/36154948 http://dx.doi.org/10.7554/eLife.80919

Ejemplares similares

Lactate metabolism is essential in early-onset mitochondrial myopathy
por: Chen, Zhenkang, et al.
Publicado: (2023)

Pathogenic mitochondrial DNA mutations inhibit melanoma metastasis
por: Shelton, Spencer D., et al.
Publicado: (2023)

α-ketobutyrate links alterations in cystine metabolism to glucose oxidation in mtDNA mutant cells
por: Lesner, Nicholas P., et al.
Publicado: (2020)

A mitofusin 2/HIF1α axis sets a maturation checkpoint in regenerating skeletal muscle
por: Wang, Xun, et al.
Publicado: (2022)

Metabolic heterogeneity in cancer
por: DeBerardinis, Ralph J
Publicado: (2014)

Q&A: Targeting metabolism to diagnose and treat cancer
por: DeBerardinis, Ralph J
Publicado: (2014)

Quantification of myocardial perfusion based on signal intensity of flow sensitized MRI
por: Abeykoon, Sumeda B, et al.
Publicado: (2012)

Pyruvate dehydrogenase activity is required for optimal growth under lipid deficient conditions
por: Rajagopalan, Kartik, et al.
Publicado: (2014)

Fundamentals of cancer metabolism
por: DeBerardinis, Ralph J., et al.
Publicado: (2016)

Quantitative myocardial perfusion in mice based on the signal intensity of flow sensitized CMR
por: Abeykoon, Sumeda, et al.
Publicado: (2012)

From “N of 1” to N of more
por: DeBerardinis, Ralph J., et al.
Publicado: (2015)

A single point mutation in the Plasmodium falciparum FtsH1 metalloprotease confers actinonin resistance
por: Goodman, Christopher D, et al.
Publicado: (2020)

In vivo isotope tracing reveals a requirement for the electron transport chain in glucose and glutamine metabolism by tumors
por: Pachnis, Panayotis, et al.
Publicado: (2022)

Vitamin B6-dependent epilepsy due to pyridoxal phosphate-binding protein (PLPBP) defect – First case report from Pakistan and review of literature
por: Ahmed, Sibtain, et al.
Publicado: (2020)

Distinct mechanisms define murine B cell lineage immunoglobulin heavy chain (IgH) repertoires
por: Yang, Yang, et al.
Publicado: (2015)

MYC promotes tryptophan uptake and metabolism by the kynurenine pathway in colon cancer
por: Venkateswaran, Niranjan, et al.
Publicado: (2019)

Autosomal recessive progeroid syndrome due to homozygosity for a TOMM7 variant
por: Garg, Abhimanyu, et al.
Publicado: (2022)

Identifying metabolomic features that predict metastasis of melanoma from a primary site
por: Shi, Xiaolei, et al.
Publicado: (2014)

A Pan-Cancer Assessment of RB1/TP53 Co-Mutations
por: Cai, Ling, et al.
Publicado: (2022)

Dissecting molecular, pathological, and clinical features associated with tumor neural/neuroendocrine heterogeneity
por: Cai, Ling, et al.
Publicado: (2023)

A Comparative Study of Neuroendocrine Heterogeneity in Small Cell Lung Cancer and Neuroblastoma
por: Cai, Ling, et al.
Publicado: (2023)

Left ventricular T2 distribution in Duchenne Muscular Dystrophy
por: Wansapura, Janaka, et al.
Publicado: (2009)

FASN deficiency induces a cytosol-to-mitochondria citrate flux to mitigate detachment-induced oxidative stress
por: Dai, Wenting, et al.
Publicado: (2023)

Serial assessment of myocardial T2 in Duchenne muscular dystrophy
por: Wansapura, Janaka, et al.
Publicado: (2011)

The abundance of metabolites related to protein methylation correlates with the metastatic capacity of human melanoma xenografts
por: Shi, Xiaolei, et al.
Publicado: (2017)

Assessing consistency across functional screening datasets in cancer cells
por: Cai, Ling, et al.
Publicado: (2021)

RNA Helicase A/DHX9 Forms Unique Cytoplasmic Antiviral Granules That Restrict Oncolytic Myxoma Virus Replication in Human Cancer Cells
por: Rahman, Masmudur M., et al.
Publicado: (2021)

Simultaneous LV pressure-volume measurement in mice with MRI and ventricular catheterization
por: Wansapura, A, et al.
Publicado: (2013)

Genomic regression analysis of coordinated expression
por: Cai, Ling, et al.
Publicado: (2017)

HIPK4 is essential for murine spermiogenesis
por: Crapster, J Aaron, et al.
Publicado: (2020)

Metabolic changes in cancer cells upon suppression of MYC
por: Anso, Elena, et al.
Publicado: (2013)

Assessment of Rapid Hepatic Glycogen Synthesis in Humans Using Dynamic (13)C Magnetic Resonance Spectroscopy
por: Stender, Stefan, et al.
Publicado: (2020)

Left ventricular T2 distribution in Duchenne Muscular Dystrophy
por: Wansapura, Janaka P, et al.
Publicado: (2010)

Assessing the validity of pressure-measuring insoles in quantifying gait variables
por: DeBerardinis, Jessica, et al.
Publicado: (2018)

Lkb1 deficiency confers glutamine dependency in polycystic kidney disease
por: Flowers, Ebony M., et al.
Publicado: (2018)

Partial N‐acetyl glutamate synthase deficiency presenting as postpartum hyperammonemia: Diagnosis and subsequent pregnancy management
por: Abou Haidar, Lea, et al.
Publicado: (2023)

Transmembrane Protease TMPRSS11B Promotes Lung Cancer Growth by Enhancing Lactate Export and Glycolytic Metabolism
por: Updegraff, Barrett L., et al.
Publicado: (2018)

Induction of LEF1 by MYC activates the WNT pathway and maintains cell proliferation
por: Hao, Yi-Heng, et al.
Publicado: (2019)

L-2-hydroxyglutaric aciduria – review of literature and case series
por: Ahmed, Sibtain, et al.
Publicado: (2023)

Use of Pressure-Measuring Insoles to Characterize Gait Parameters in Simulated Reduced-Gravity Conditions
por: Ison, Christian, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_j5r5au3hkn2bmpt7g3ve0l22c8