Anti-interleukin-6 Antibody Clazakizumab in Antibody-mediated Kidney Transplant Rejection: Effect on Donor-derived Cell-free DNA and C-X-C Motif Chemokine Ligand 10

Targeting interleukin-6 (IL-6) was shown to counteract donor-specific antibody production and antibody-mediated rejection (AMR) activity. It is not known whether, or to what extent, IL-6 antagonism modulates biomarkers indicative of tissue damage (donor-derived cell-free DNA [dd-cfDNA]) and parenchy...

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Detalles Bibliográficos
Autores principales: Mayer, Katharina A., Doberer, Konstantin, Halloran, Philip F., Budde, Klemens, Haindl, Susanne, Mühlbacher, Jakob, Eskandary, Farsad, Viard, Thierry, Casas, Silvia, Jilma, Bernd, Böhmig, Georg A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Kidney Transplantation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9649278/
https://www.ncbi.nlm.nih.gov/pubmed/36382130
http://dx.doi.org/10.1097/TXD.0000000000001406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9649278/
https://www.ncbi.nlm.nih.gov/pubmed/36382130
http://dx.doi.org/10.1097/TXD.0000000000001406

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