Cargando…

Anti-interleukin-6 Antibody Clazakizumab in Antibody-mediated Kidney Transplant Rejection: Effect on Donor-derived Cell-free DNA and C-X-C Motif Chemokine Ligand 10

Targeting interleukin-6 (IL-6) was shown to counteract donor-specific antibody production and antibody-mediated rejection (AMR) activity. It is not known whether, or to what extent, IL-6 antagonism modulates biomarkers indicative of tissue damage (donor-derived cell-free DNA [dd-cfDNA]) and parenchy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mayer, Katharina A., Doberer, Konstantin, Halloran, Philip F., Budde, Klemens, Haindl, Susanne, Mühlbacher, Jakob, Eskandary, Farsad, Viard, Thierry, Casas, Silvia, Jilma, Bernd, Böhmig, Georg A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2022
Materias:	Kidney Transplantation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9649278/ https://www.ncbi.nlm.nih.gov/pubmed/36382130 http://dx.doi.org/10.1097/TXD.0000000000001406

Ejemplares similares

Clazakizumab in late antibody-mediated rejection: study protocol of a randomized controlled pilot trial
por: Eskandary, Farsad, et al.
Publicado: (2019)

Anti‐interleukin‐6 antibody clazakizumab in late antibody‐mediated kidney transplant rejection: effect on cytochrome P450 drug metabolism
por: Mühlbacher, Jakob, et al.
Publicado: (2021)

Complement Markers in Blood and Urine: No Diagnostic Value in Late Silent Antibody-Mediated Rejection
por: Mező, Blanka, et al.
Publicado: (2019)

High-activity Classical and Alternative Complement Pathway Genotypes—Association With Donor-specific Antibody-triggered Injury and Renal Allograft Survival
por: Mező, Blanka, et al.
Publicado: (2020)

Non-invasive Chemokine Detection: Improved Prediction of Antibody-Mediated Rejection in Donor-Specific Antibody-Positive Renal Allograft Recipients
por: Mühlbacher, Jakob, et al.
Publicado: (2020)

The therapeutic challenge of late antibody‐mediated kidney allograft rejection
por: Böhmig, Georg A., et al.
Publicado: (2019)

Rituximab in Combination With Bortezomib, Plasmapheresis, and High-Dose IVIG to Treat Antibody-Mediated Renal Allograft Rejection
por: Waiser, Johannes, et al.
Publicado: (2016)

Hyperacute Antibody-mediated Rejection Associated With Red Blood Cell Antibodies
por: Shaw, James, et al.
Publicado: (2019)

Magnetic Resonance Imaging for Evaluation of Interstitial Fibrosis in Kidney Allografts
por: Beck-Tölly, Andrea, et al.
Publicado: (2020)

Diagnostic value of donor‐derived cell‐free DNA to predict antibody‐mediated rejection in donor‐specific antibody‐positive renal allograft recipients
por: Mayer, Katharina A., et al.
Publicado: (2021)

Rituximab and Monitoring Strategies for Late Antibody-Mediated Rejection After Kidney Transplantation
por: Parajuli, Sandesh, et al.
Publicado: (2017)

Donor-derived Cell-free DNA Identifies Antibody-mediated Rejection in Donor Specific Antibody Positive Kidney Transplant Recipients
por: Jordan, Stanley C., et al.
Publicado: (2018)

The Role of Complement Split-products as Biomarkers for Acute Antibody-mediated Rejection of Kidney Allografts
por: Abu Jawdeh, Bassam G., et al.
Publicado: (2022)

Circulating B Cells With Memory and Antibody-Secreting Phenotypes Are Detectable in Pediatric Kidney Transplant Recipients Before the Development of Antibody-Mediated Rejection
por: Fischman, Clara, et al.
Publicado: (2019)

A Combined microRNA and Chemokine Profile in Urine to Identify Rejection After Kidney Transplantation
por: Gielis, Els M., et al.
Publicado: (2021)

Efficacy and Safety of Tocilizumab in the Treatment of Acute Active Antibody-mediated Rejection in Kidney Transplant Recipients
por: Pottebaum, April A., et al.
Publicado: (2020)

Class and Kinetics of Weakly Reactive Pretransplant Donor-specific HLA Antibodies Predict Rejection in Kidney Transplant Recipients
por: Morrison, Alexander H., et al.
Publicado: (2019)

Treatment of Chronic Active Antibody-mediated Rejection With Pulse Steroids, IVIG, With or Without Rituximab is Associated With Increased Risk of Pneumonia
por: Joachim, Emily, et al.
Publicado: (2020)

Chronic Active Antibody-mediated Rejection in Kidney Transplant Recipients: Treatment Response Rates and Value of Early Surveillance Biopsies
por: Aziz, Fahad, et al.
Publicado: (2022)

The Trend of Serum Creatinine Does Not Predict Follow-Up Biopsy Findings Among Kidney Transplant Recipients With Antibody-Mediated Rejection
por: Parajuli, Sandesh, et al.
Publicado: (2023)

Assessment of 4 Cases of Kidney Transplantation from Hepatitis C Virus Antibody-Positive and RNA-Negative Donors to Antibody-Negative Recipients
por: Unagami, Kohei, et al.
Publicado: (2016)

Association Between Peripheral Blood CD19-Positive Rate and Antibody-Mediated Rejection Following Rituximab Administration in Kidney Transplant Recipients
por: Nanmoku, Koji, et al.
Publicado: (2019)

Increased Autoantibodies Against Ro/SS-A, CENP-B, and La/SS-B in Patients With Kidney Allograft Antibody-mediated Rejection
por: Clotet-Freixas, Sergi, et al.
Publicado: (2021)

Cytokine Profiles in Children After Pediatric Kidney Transplantation With Acute Cellular Compared to Chronic Antibody-mediated Rejection and Stable Patients: A Pilot Study
por: Borsum, Nadja, et al.
Publicado: (2019)

Safety, tolerability, and efficacy of monoclonal CD38 antibody felzartamab in late antibody-mediated renal allograft rejection: study protocol for a phase 2 trial
por: Mayer, Katharina A., et al.
Publicado: (2022)

Noninvasive Diagnosis of Acute Rejection in Renal Transplant Patients Using Mass Spectrometric Analysis of Urine Samples: A Multicenter Diagnostic Phase III Trial
por: Gwinner, Wilfried, et al.
Publicado: (2022)

Kidney Rejection Following Simultaneous Liver-kidney Transplantation
por: Shah, Sapna, et al.
Publicado: (2020)

Absolute or Relative Quantification of Donor-derived Cell-free DNA in Kidney Transplant Recipients: Case Series
por: Osmanodja, Bilgin, et al.
Publicado: (2021)

Alloreactive T cells to Assess Acute Rejection Risk in Kidney Transplant Recipients
por: Mendoza Rojas, Aleixandra, et al.
Publicado: (2023)

Acute Rejection Phenotypes in the Current Era of Immunosuppression: A Single-Center Analysis
por: Wehmeier, Caroline, et al.
Publicado: (2017)

Technical Considerations and Confounders for Urine CXCL10 Chemokine Measurement
por: Handschin, Joelle, et al.
Publicado: (2019)

Acute Rejection After Kidney Transplantation Associates With Circulating MicroRNAs and Vascular Injury
por: Bijkerk, Roel, et al.
Publicado: (2017)

Mast Cells in Kidney Transplant Biopsies With Borderline T Cell-mediated Rejection and Their Relation to Chronicity
por: Varol, Hilal, et al.
Publicado: (2023)

Immunomics of Renal Allograft Acute T Cell-Mediated Rejection Biopsies of Tacrolimus- and Belatacept-Treated Patients
por: van der Zwan, Marieke, et al.
Publicado: (2018)

Acute Kidney Allograft Rejection Following Coronavirus mRNA Vaccination: A Case Report
por: Bau, Jason T., et al.
Publicado: (2022)

Absence of Intragraft B Cells in Rejection Biopsies After Rituximab Induction Therapy: Consequences for Clinical Outcome
por: van den Hoogen, Martijn W.F., et al.
Publicado: (2017)

Response to Treatment for Chronic-active T Cell–mediated Rejection in Kidney Transplantation: A Report of 3 Cases
por: Noguchi, Hiroshi, et al.
Publicado: (2020)

Rejection-associated Phenotype of De Novo Thrombotic Microangiopathy Represents a Risk for Premature Graft Loss
por: Petr, Vojtech, et al.
Publicado: (2021)

How Should Acute T-cell Mediated Rejection of Kidney Transplants Be Treated: Importance of Follow-up Biopsy
por: Aziz, Fahad, et al.
Publicado: (2022)

Levels of donor‐derived cell‐free DNA and chemokines in BK polyomavirus‐associated nephropathy
por: Mayer, Katharina A., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_rp6kqhmg5qdutf25o8fbvqnhfq