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Snowflake epitope matching correlates with child-specific antibodies during pregnancy and donor-specific antibodies after kidney transplantation

Development of donor-specific human leukocyte antigen (HLA) antibodies (DSA) remains a major risk factor for graft loss following organ transplantation, where DSA are directed towards patches on the three-dimensional structure of the respective organ donor’s HLA proteins. Matching donors and recipie...

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Detalles Bibliográficos
Autores principales: Niemann, Matthias, Strehler, Yara, Lachmann, Nils, Halleck, Fabian, Budde, Klemens, Hönger, Gideon, Schaub, Stefan, Matern, Benedict M., Spierings, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9649433/
https://www.ncbi.nlm.nih.gov/pubmed/36389845
http://dx.doi.org/10.3389/fimmu.2022.1005601