A system pharmacology Boolean network model for the TLR4-mediated inflammatory response in early sepsis

Sepsis is a life-threatening condition driven by the dysregulation of the host immune response to an infection. The complex and interacting mechanisms underlying sepsis remain not fully understood. By integrating prior knowledge from literature using mathematical modelling techniques, we aimed to ob...

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Detalles Bibliográficos
Autores principales: Liu, Feiyan, Aulin, Linda B. S., Kossen, Sebastiaan S. A., Cathalina, Julius, Bremmer, Marlotte, Foks, Amanda C., van der Graaf, Piet H., Moerland, Matthijs, van Hasselt, Johan G. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9649476/
https://www.ncbi.nlm.nih.gov/pubmed/36261775
http://dx.doi.org/10.1007/s10928-022-09828-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9649476/
https://www.ncbi.nlm.nih.gov/pubmed/36261775
http://dx.doi.org/10.1007/s10928-022-09828-6

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