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Extract of Mallotus oppositifolius (Geiseler) Müll. Arg. increased prefrontal cortex dendritic spine density and serotonin and attenuated para-chlorophenylalanine-aggravated aggressive and depressive behaviors in mice
Background/Aim: Depression-related aggression is linked to serotonin (5-HT) and dendritic spine alterations. Although Mallotus oppositifolius extract (MOE) has potential for reducing this effect, its specific role remains uncertain. Herein, we evaluated this potential and associated alterations in t...
Autores principales: | Kukuia, Kennedy K.E., Appiah, Frimpong, Dugbartey, George J., Takyi, Yaw F., Amoateng, Patrick, Amponsah, Seth K., Adi-Dako, Ofosua, Koomson, Awo E., Ayertey, Frederick, Adutwum-Ofosu, Kevin K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9649488/ https://www.ncbi.nlm.nih.gov/pubmed/36386158 http://dx.doi.org/10.3389/fphar.2022.962549 |
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