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Screening of traditional Chinese medicine monomers as ribonucleotide reductase M2 inhibitors for tumor treatment

BACKGROUND: Ribonucleotide reductase (RR) is a key enzyme in tumor proliferation, especially its subunit-RRM2. Although there are multiple therapeutics for tumors, they all have certain limitations. Given their advantages, traditional Chinese medicine (TCM) monomers have become an important source o...

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Detalles Bibliográficos
Autores principales: Qin, Ya-Ya, Feng, Song, Zhang, Xiao-Dong, Peng, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9649558/
https://www.ncbi.nlm.nih.gov/pubmed/36387821
http://dx.doi.org/10.12998/wjcc.v10.i31.11299