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Fusion and expansion of vitellogenin vesicles during Caenorhabditis elegans intestinal senescence

Some of the most conspicuous aging phenotypes of C. elegans are related to post‐reproductive production of vitellogenins (Vtg), which form yolk protein (YP) complexes after processing and lipid loading. Vtg/YP levels show huge increases with age, and inhibition of this extends lifespan, but how subc...

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Detalles Bibliográficos
Autores principales: Zhai, Chao, Zhang, Nan, Li, Xi‐Xia, Chen, Xi, Sun, Fei, Dong, Meng‐Qiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9649609/
https://www.ncbi.nlm.nih.gov/pubmed/36199214
http://dx.doi.org/10.1111/acel.13719