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Identification of hub genes and transcription factor regulatory network for heart failure using RNA-seq data and robust rank aggregation analysis

BACKGROUND: Heart failure (HF) is the end stage of various cardiovascular diseases with a high mortality rate. Novel diagnostic and therapeutic biomarkers for HF are urgently required. Our research aims to identify HF-related hub genes and regulatory networks using bioinformatics and validation assa...

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Detalles Bibliográficos
Autores principales: Tu, Dingyuan, Ma, Chaoqun, Zeng, ZhenYu, Xu, Qiang, Guo, Zhifu, Song, Xiaowei, Zhao, Xianxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9649652/
https://www.ncbi.nlm.nih.gov/pubmed/36386304
http://dx.doi.org/10.3389/fcvm.2022.916429