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Single cell profiling of primary and paired metastatic lymph node tumors in breast cancer patients

The microenvironment of lymph node metastasized tumors (LNMT) determines tumor progression and response to therapy, but a systematic study of LNMT is lacking. Here, we generate single-cell maps of primary tumors (PTs) and paired LNMTs in 8 breast cancer patients. We demonstrate that the activation,...

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Detalles Bibliográficos
Autores principales:	Liu, Tong, Liu, Cheng, Yan, Meisi, Zhang, Lei, Zhang, Jing, Xiao, Min, Li, Zhigao, Wei, Xiaofan, Zhang, Hongquan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9649678/ https://www.ncbi.nlm.nih.gov/pubmed/36357424 http://dx.doi.org/10.1038/s41467-022-34581-2

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